| Regenerative Therapies in the Management of Chronic Low Back Pain from Evidence to Practice: An Analytical Summary of the 2025 Comprehensive Evidence-Based Guidelines |
Back Pain & Disc Disease |
Clinical |
Guidelines & Consensus |
Manchikanti L |
2026 |
42804305 ↗ |
| Comprehensive Evidence-Based Guidelines for Regenerative Therapies in the Management of Chronic Low Back Pain: 2025 Update from the American Society Of Interventional Pain Physicians (ASIPP) |
Back Pain & Disc Disease |
Clinical |
Guidelines & Consensus |
Manchikanti L |
2025 |
41481869 ↗ |
| A consensus statement addressing mesenchymal stem cell transplantation for multiple sclerosis: it's time! |
Brain, Nerves & Neurological Conditions |
Clinical |
Guidelines & Consensus |
Siatskas C |
2010 |
20665128 ↗ |
| Platelet-rich plasma and stem cell therapies for spondylosis: a systematic review of randomized controlled trials |
Back Pain & Disc Disease |
Clinical |
Systematic Review / Meta-analysis |
Zhang RE |
2026 |
42141193 ↗ |
| Stromal cell-based injection therapies for the treatment of knee osteoarthritis: A systematic review of level I randomized controlled trials |
Knee Arthritis |
Clinical |
Systematic Review / Meta-analysis |
Dhillon J |
2025 |
40290651 ↗ |
| Mesenchymal Stromal Cells for the Treatment of Discogenic Low Back Pain: A Systematic Review of Clinical Studies |
Back Pain & Disc Disease |
Clinical |
Systematic Review / Meta-analysis |
Vadalà G |
2025 |
41508590 ↗ |
| Effect of mesenchymal stromal cells transplantation on the outcomes of patients with knee osteoarthritis: A systematic review and meta-analysis |
Knee Arthritis |
Clinical |
Systematic Review / Meta-analysis |
Xie RH |
2024 |
37991925 ↗ |
| Hematopoietic cell-based and non-hematopoietic cell-based strategies for immune tolerance induction in living-donor renal transplantation: A systematic review |
Transplant & Blood Disorders |
Clinical |
Systematic Review / Meta-analysis |
Annamalai C |
2023 |
37709652 ↗ |
| Stem cell-based interventions for the treatment of stroke in newborn infants |
Brain, Nerves & Neurological Conditions |
Clinical |
Systematic Review / Meta-analysis |
Bruschettini M |
2023 |
37994736 ↗ |
| Effect of Stem Cell Injections on Osteoarthritis-related Structural Outcomes: A Systematic Review |
Knee Arthritis; Hip, Shoulder & Other Joints |
Clinical |
Systematic Review / Meta-analysis |
Gong J |
2021 |
33004537 ↗ |
| Stem cell-based interventions for the prevention of morbidity and mortality following hypoxic-ischaemic encephalopathy in newborn infants |
Brain, Nerves & Neurological Conditions |
Clinical |
Systematic Review / Meta-analysis |
Bruschettini M |
2020 |
32813884 ↗ |
| Intraarticular injection of bone marrow-derived mesenchymal stem cells enhances regeneration in knee osteoarthritis |
Knee Arthritis |
Clinical |
Systematic Review / Meta-analysis |
Doyle EC |
2020 |
32006075 ↗ |
| Cell-based therapy to reduce mortality from COVID-19: Systematic review and meta-analysis of human studies on acute respiratory distress syndrome |
Other Areas of MSC Research |
Clinical |
Systematic Review / Meta-analysis |
Qu W |
2020 |
32472653 ↗ |
| Exploring the Most Promising Stem Cell Therapy in Liver Failure: A Systematic Review |
Other Areas of MSC Research |
Clinical |
Systematic Review / Meta-analysis |
AdiwinataPawitan J |
2019 |
31871465 ↗ |
| Mesenchymal stromal cells as treatment or prophylaxis for acute or chronic graft-versus-host disease in haematopoietic stem cell transplant (HSCT) recipients with a haematological condition |
Transplant & Blood Disorders |
Clinical |
Systematic Review / Meta-analysis |
Fisher SA |
2019 |
30697701 ↗ |
| Towards Standardized Stem Cell Therapy in Type 2 Diabetes Mellitus: A Systematic Review |
Other Areas of MSC Research |
Clinical |
Systematic Review / Meta-analysis |
Pawitan JA |
2018 |
29732994 ↗ |
| Efficacy and safety of mesenchymal stromal cells for the prophylaxis of chronic graft-versus-host disease after allogeneic hematopoietic stem cell transplantation: a meta-analysis of randomized controlled trials |
Transplant & Blood Disorders; Safety & Side Effects |
Clinical |
Systematic Review / Meta-analysis |
Wang L |
2018 |
29947972 ↗ |
| Application of selected scaffolds for bone tissue engineering: a systematic review |
Bone Healing & Osteonecrosis; Cell Quality, Manufacturing & Delivery |
Clinical |
Systematic Review / Meta-analysis |
Hosseinpour S |
2017 |
28194530 ↗ |
| Heterogeneity in Studies of Mesenchymal Stromal Cells to Treat or Prevent Graft-versus-Host Disease: A Scoping Review of the Evidence |
Transplant & Blood Disorders |
Clinical |
Systematic Review / Meta-analysis |
Rizk M |
2016 |
27130504 ↗ |
| Treatment with Allogeneic Mesenchymal Stromal Cells for Moderate to Severe Acute Respiratory Distress Syndrome: A Double-Blind, Placebo-controlled, Multicenter Phase 2b Clinical Trial (STAT) |
Other Areas of MSC Research |
Clinical |
Randomized Controlled Trial |
Matthay MA |
2026 |
40728562 ↗ |
| Randomized phase 2b dose-escalation trial of stem cell therapy with laromestrocel for aging frailty |
Other Areas of MSC Research |
Clinical |
Randomized Controlled Trial |
Ruiz JG |
2026 |
41747733 ↗ |
| Bone Marrow Aspirate Concentrate Improves the Early Osseous Integration of Fresh Osteochondral Allografts in the Knee: A Randomized Controlled Trial |
Knee Arthritis; Hip, Shoulder & Other Joints |
Clinical |
Randomized Controlled Trial |
Gelber PE |
2026 |
41992571 ↗ |
| Intra-Articular Injection of Human Bone Marrow-Derived Mesenchymal Stem Cells in Knee Osteoarthritis: A Randomized, Double-Blind, Controlled Trial |
Knee Arthritis |
Clinical |
Randomized Controlled Trial |
Lee BW |
2025 |
39874108 ↗ |
| Allogeneic mesenchymal stem cell therapy with laromestrocel in mild Alzheimer's disease: a randomized controlled phase 2a trial |
Brain, Nerves & Neurological Conditions |
Clinical |
Randomized Controlled Trial |
Rash BG |
2025 |
40065171 ↗ |
| Prospective Double-Blind Randomized Study of Single Dose Bone Marrow-Derived Mesenchymal Stromal Cells versus Placebo for Steroid-Refractory Acute Graft-Versus-Host Disease |
Transplant & Blood Disorders |
Clinical |
Randomized Controlled Trial |
Ringdén O |
2025 |
41384258 ↗ |
| The role of adipose-derived stem cells in knee osteoarthritis treatment: insights from a triple-blind clinical study |
Knee Arthritis |
Clinical |
Randomized Controlled Trial |
Sajadi S |
2025 |
40369655 ↗ |
| Allogeneic Bone Marrow-Derived Mesenchymal Stem Cells for Parkinson's Disease: A Randomized Trial |
Brain, Nerves & Neurological Conditions |
Clinical |
Randomized Controlled Trial |
Schiess MC |
2025 |
40891094 ↗ |
| Combined treatment with mesenchymal stem cells and therapeutic hypothermia for neonatal hypoxic ischemic encephalopathy: a phase 1/2 randomized trial |
Brain, Nerves & Neurological Conditions |
Clinical |
Randomized Controlled Trial |
Wada K |
2025 |
40348804 ↗ |
| Treatment of non-hypertrophic pseudoarthrosis of long bones with a Tissue Engineered Product loaded with autologous bone marrow-derived Mesenchymal Stromal Cells: Results from a phase IIa, prospective, randomized, parallel, pilot clinical trial comparing to iliac crest autograft |
Bone Healing & Osteonecrosis; Cell Quality, Manufacturing & Delivery |
Clinical |
Randomized Controlled Trial |
Chaverri D |
2024 |
38797000 ↗ |
| Allogenic bone marrow-derived mesenchymal stromal cell-based therapy for patients with chronic low back pain: a prospective, multicentre, randomised placebo controlled trial (RESPINE study) |
Back Pain & Disc Disease |
Clinical |
Randomized Controlled Trial |
Pers YM |
2024 |
39393844 ↗ |
| Efficacy and Safety of Stempeucel in Osteoarthritis of the Knee: A Phase 3 Randomized, Double-Blind, Multicenter, Placebo-Controlled Study |
Knee Arthritis; Safety & Side Effects |
Clinical |
Randomized Controlled Trial |
Gupta PK |
2023 |
37366164 ↗ |
| Clinical efficacy and safety of multipotent adult progenitor cells (invimestrocel) for acute respiratory distress syndrome (ARDS) caused by pneumonia: a randomized, open-label, standard therapy-controlled, phase 2 multicenter study (ONE-BRIDGE) |
Other Areas of MSC Research; Safety & Side Effects |
Clinical |
Randomized Controlled Trial |
Ichikado K |
2023 |
37608287 ↗ |
| Cell-based versus corticosteroid injections for knee pain in osteoarthritis: a randomized phase 3 trial |
Knee Arthritis |
Clinical |
Randomized Controlled Trial |
Mautner K |
2023 |
37919438 ↗ |
| Intravenous transplantation of bone marrow-derived mesenchymal stromal cells in patients with multiple sclerosis, a phase I/IIa, double blind, randomized controlled study |
Brain, Nerves & Neurological Conditions |
Clinical |
Randomized Controlled Trial |
Nabavi SM |
2023 |
37515913 ↗ |
| Safety and Preliminary Efficacy of Mesenchymal Stromal Cell (ORBCEL-M) Therapy in Diabetic Kidney Disease: A Randomized Clinical Trial (NEPHSTROM) |
Other Areas of MSC Research; Safety & Side Effects |
Clinical |
Randomized Controlled Trial |
Perico N |
2023 |
37560967 ↗ |
| Role of mesenchymal stromal cells derivatives in diabetic foot ulcers: a controlled randomized phase 1/2 clinical trial |
Wound Healing & Skin Conditions; Cell Sources & Treatment Comparisons |
Clinical |
Randomized Controlled Trial |
Arango-Rodríguez ML |
2022 |
36084965 ↗ |
| Third-party bone marrow-derived mesenchymal stromal cell infusion before liver transplantation: A randomized controlled trial |
Transplant & Blood Disorders |
Clinical |
Randomized Controlled Trial |
Casiraghi F |
2021 |
33370477 ↗ |
| Ankle osteonecrosis in fifty-one children and adolescent's leukemia survivors: a prospective randomized study on percutaneous mesenchymal stem cells treatment |
Hip, Shoulder & Other Joints; Bone Healing & Osteonecrosis |
Clinical |
Randomized Controlled Trial |
Hernigou P |
2021 |
33893522 ↗ |
| Effect of mesenchymal stromal cell infusions on lung function in COPD patients with high CRP levels |
Other Areas of MSC Research |
Clinical |
Randomized Controlled Trial |
Weiss DJ |
2021 |
33964910 ↗ |
| Randomized clinical trial: expanded autologous bone marrow mesenchymal cells combined with allogeneic bone tissue, compared with autologous iliac crest graft in lumbar fusion surgery |
Back Pain & Disc Disease |
Clinical |
Randomized Controlled Trial |
García de Frutos A |
2020 |
32730985 ↗ |
| A Phase 3 Randomized Study of Remestemcel-L versus Placebo Added to Second-Line Therapy in Patients with Steroid-Refractory Acute Graft-versus-Host Disease |
Transplant & Blood Disorders |
Clinical |
Randomized Controlled Trial |
Kebriaei P |
2020 |
31505228 ↗ |
| Allogeneic Mesenchymal Cell Therapy in Anthracycline-Induced Cardiomyopathy Heart Failure Patients: The CCTRN SENECA Trial |
Heart & Circulation |
Clinical |
Randomized Controlled Trial |
Bolli R |
2020 |
33403362 ↗ |
| Treatment with allogeneic mesenchymal stromal cells for moderate to severe acute respiratory distress syndrome (START study): a randomised phase 2a safety trial |
Other Areas of MSC Research; Safety & Side Effects |
Clinical |
Randomized Controlled Trial |
Matthay MA |
2019 |
30455077 ↗ |
| Comparison of Mesenchymal Stem Cell Efficacy in Ischemic Versus Nonischemic Dilated Cardiomyopathy |
Heart & Circulation |
Clinical |
Randomized Controlled Trial |
Tompkins BA |
2018 |
30005555 ↗ |
| Safety and Efficacy of the Intravenous Infusion of Umbilical Cord Mesenchymal Stem Cells in Patients With Heart Failure: A Phase 1/2 Randomized Controlled Trial (RIMECARD Trial [Randomized Clinical Trial of Intravenous Infusion Umbilical Cord Mesenchymal Stem Cells on Cardiopathy]) |
Heart & Circulation; Safety & Side Effects |
Clinical |
Randomized Controlled Trial |
Bartolucci J |
2017 |
28974553 ↗ |
| Dose Comparison Study of Allogeneic Mesenchymal Stem Cells in Patients With Ischemic Cardiomyopathy (The TRIDENT Study) |
Heart & Circulation; Cell Quality, Manufacturing & Delivery |
Clinical |
Randomized Controlled Trial |
Florea V |
2017 |
28923793 ↗ |
| Randomized Comparison of Allogeneic Versus Autologous Mesenchymal Stem Cells for Nonischemic Dilated Cardiomyopathy: POSEIDON-DCM Trial |
Heart & Circulation |
Clinical |
Randomized Controlled Trial |
Hare JM |
2017 |
27856208 ↗ |
| Allogeneic bone marrow-derived mesenchymal stromal cells for hepatitis B virus-related acute-on-chronic liver failure: A randomized controlled trial |
Other Areas of MSC Research |
Clinical |
Randomized Controlled Trial |
Lin BL |
2017 |
28370357 ↗ |
| Intervertebral Disc Repair by Allogeneic Mesenchymal Bone Marrow Cells: A Randomized Controlled Trial |
Back Pain & Disc Disease |
Clinical |
Randomized Controlled Trial |
Noriega DC |
2017 |
27661661 ↗ |
| Efficacy and safety of adult human bone marrow-derived, cultured, pooled, allogeneic mesenchymal stromal cells (Stempeucel®): preclinical and clinical trial in osteoarthritis of the knee joint |
Knee Arthritis; Safety & Side Effects |
Clinical |
Randomized Controlled Trial |
Gupta PK |
2016 |
27993154 ↗ |
| Allogeneic Mesenchymal Precursor Cells (MPC) in Diabetic Nephropathy: A Randomized, Placebo-controlled, Dose Escalation Study |
Other Areas of MSC Research |
Clinical |
Randomized Controlled Trial |
Packham DK |
2016 |
27743903 ↗ |
| Randomized, double-blind, phase I/II study of intravenous allogeneic mesenchymal stromal cells in acute myocardial infarction |
Heart & Circulation |
Clinical |
Randomized Controlled Trial |
Chullikana A |
2015 |
25484310 ↗ |
| Allogeneic Bone Marrow-Derived Mesenchymal Stromal Cells Promote Healing of Refractory Perianal Fistulas in Patients With Crohn's Disease |
Other Areas of MSC Research |
Clinical |
Randomized Controlled Trial |
Molendijk I |
2015 |
26116801 ↗ |
| Allogeneic Mesenchymal Precursor Cells in Type 2 Diabetes: A Randomized, Placebo-Controlled, Dose-Escalation Safety and Tolerability Pilot Study |
Other Areas of MSC Research; Safety & Side Effects |
Clinical |
Randomized Controlled Trial |
Skyler JS |
2015 |
26153271 ↗ |
| Treatment of Knee Osteoarthritis With Allogeneic Bone Marrow Mesenchymal Stem Cells: A Randomized Controlled Trial |
Knee Arthritis |
Clinical |
Randomized Controlled Trial |
Vega A |
2015 |
25822648 ↗ |
| Allograft alone versus allograft with bone marrow concentrate for the healing of the instrumented posterolateral lumbar fusion |
Back Pain & Disc Disease |
Clinical |
Randomized Controlled Trial |
Hart R |
2014 |
24361998 ↗ |
| A double-blind placebo-controlled clinical evaluation of MultiStem for the treatment of ischemic stroke |
Brain, Nerves & Neurological Conditions |
Clinical |
Randomized Controlled Trial |
Hess DC |
2014 |
23692637 ↗ |
| A double blind randomized placebo controlled phase I/II study assessing the safety and efficacy of allogeneic bone marrow derived mesenchymal stem cell in critical limb ischemia |
Heart & Circulation; Safety & Side Effects |
Clinical |
Randomized Controlled Trial |
Gupta PK |
2013 |
23758736 ↗ |
| A placebo-controlled, randomized trial of mesenchymal stem cells in COPD |
Other Areas of MSC Research |
Clinical |
Randomized Controlled Trial |
Weiss DJ |
2013 |
23172272 ↗ |
| Comparison of allogeneic vs autologous bone marrow–derived mesenchymal stem cells delivered by transendocardial injection in patients with ischemic cardiomyopathy: the POSEIDON randomized trial |
Heart & Circulation |
Clinical |
Randomized Controlled Trial |
Hare JM |
2012 |
23117550 ↗ |
| A randomized, double-blind, placebo-controlled, dose-escalation study of intravenous adult human mesenchymal stem cells (prochymal) after acute myocardial infarction |
Heart & Circulation |
Clinical |
Randomized Controlled Trial |
Hare JM |
2009 |
19958962 ↗ |
| MesenSistem-EB: systemic haploidentical mesenchymal stem cell therapy in recessive dystrophic epidermolysis bullosa associated with clinical benefits and correlated with MCP1 and sCD40L dynamics |
Wound Healing & Skin Conditions |
Clinical |
Early-Phase / Non-randomized Trial |
Maseda R |
2026 |
42164509 ↗ |
| Intradiscal injection of allogeneic bone marrow derived clonal mesenchymal stromal cells in discogenic low back pain: a phase I study on safety and feasibility (RELIEF: phase I) |
Back Pain & Disc Disease; Safety & Side Effects |
Clinical |
Early-Phase / Non-randomized Trial |
Maal AB |
2025 |
41024309 ↗ |
| Allogeneic bone marrow-derived mesenchymal stem cells in the aging kidney: secondary results of a Parkinson's disease clinical trial |
Brain, Nerves & Neurological Conditions |
Clinical |
Early-Phase / Non-randomized Trial |
Martinez-Lemus JD |
2025 |
40993774 ↗ |
| Clinical trial assessing the safety and efficacy of human bone marrow-derived allogeneic mesenchymal stem cell therapy for chronic active antibody-mediated rejection in kidney transplant recipients |
Transplant & Blood Disorders; Safety & Side Effects |
Clinical |
Early-Phase / Non-randomized Trial |
Park H |
2025 |
40663031 ↗ |
| Intra-articular delivery of allogeneic bone marrow derived mesenchymal stromal cells (BM-MSCs) for painful lumbar facet arthropathy: a phase I clinical trial |
Back Pain & Disc Disease |
Clinical |
Early-Phase / Non-randomized Trial |
Qu W |
2025 |
41163019 ↗ |
| Therapeutic role of mesenchymal stem cells in second-degree burn wound repair: Integration with split-thickness skin grafts |
Wound Healing & Skin Conditions |
Clinical |
Early-Phase / Non-randomized Trial |
Schulman CI |
2025 |
40727091 ↗ |
| Safety of subconjunctival injection of mesenchymal stromal cells in persistent corneal epithelial disease – A phase 1b clinical trial |
Other Areas of MSC Research; Safety & Side Effects |
Clinical |
Early-Phase / Non-randomized Trial |
Tu GC |
2025 |
40414287 ↗ |
| A phase I/II clinical trial of ex-vivo expanded human bone marrow derived allogeneic mesenchymal stromal cells in adult patients with perianal fistulizing Crohn's Disease |
Other Areas of MSC Research |
Clinical |
Early-Phase / Non-randomized Trial |
Swaroop S |
2024 |
38745184 ↗ |
| CellKine clinical trial: first report from a phase 1 trial of allogeneic bone marrow-derived mesenchymal stem cells in subjects with painful lumbar facet joint arthropathy |
Back Pain & Disc Disease |
Clinical |
Early-Phase / Non-randomized Trial |
Yan D |
2024 |
39300992 ↗ |
| Safety and potential efficacy of expanded mesenchymal stromal cells of bone marrow and umbilical cord origins in patients with chronic spinal cord injuries: a phase I/II study |
Brain, Nerves & Neurological Conditions; Safety & Side Effects; Cell Sources & Treatment Comparisons |
Clinical |
Early-Phase / Non-randomized Trial |
Awidi A |
2024 |
38703153 ↗ |
| Mesenchymal Stem Cell Therapy in Acute Intracerebral Hemorrhage: A Dose-Escalation Safety and Tolerability Trial |
Brain, Nerves & Neurological Conditions; Safety & Side Effects |
Clinical |
Early-Phase / Non-randomized Trial |
Durand NC |
2024 |
38114796 ↗ |
| Allogenic MSC infusion in kidney transplantation recipients promotes within 4 hours distinct B cell and T cell phenotypes |
Transplant & Blood Disorders; How MSCs Work |
Clinical |
Early-Phase / Non-randomized Trial |
Hendriks SH |
2024 |
39450174 ↗ |
| Allogeneic bone marrow derived clonal mesenchymal stromal cells in refractory rheumatoid arthritis: a pilot study |
Autoimmune & Inflammatory Conditions |
Clinical |
Early-Phase / Non-randomized Trial |
Jamshidi A |
2024 |
39713986 ↗ |
| Pulmonary and Systemic Immune Profiles Following Lung Volume Reduction Surgery and Allogeneic Mesenchymal Stromal Cell Treatment in Emphysema |
Other Areas of MSC Research |
Clinical |
Early-Phase / Non-randomized Trial |
Jia L |
2024 |
39404398 ↗ |
| Repeated Infusions of Bone-Marrow-Derived Mesenchymal Stem Cells over 8 Weeks for Steroid-Refractory Chronic Graft-versus-Host Disease: A Prospective, Phase I/II Clinical Study |
Transplant & Blood Disorders; Cell Quality, Manufacturing & Delivery |
Clinical |
Early-Phase / Non-randomized Trial |
Kim N |
2024 |
38928436 ↗ |
| A phase IB/IIA study of ex vivo expanded allogeneic bone marrow-derived mesenchymal stem cells for the treatment of rectovaginal fistulizing Crohn's disease |
Other Areas of MSC Research |
Clinical |
Early-Phase / Non-randomized Trial |
Lightner AL |
2024 |
37661485 ↗ |
| Treatment of post-allogeneic hematopoietic stem cell transplant cytopenias with sequential doses of multipotent mesenchymal stromal/stem cells |
Transplant & Blood Disorders; Cell Quality, Manufacturing & Delivery |
Clinical |
Early-Phase / Non-randomized Trial |
Navarro-Bailón A |
2024 |
38727653 ↗ |
| Phase 1/2 trials of human bone marrow-derived clonal mesenchymal stem cells for treatment of adults with moderate to severe atopic dermatitis |
Wound Healing & Skin Conditions |
Clinical |
Early-Phase / Non-randomized Trial |
Seo HM |
2024 |
38944393 ↗ |
| A novel therapeutic management for diabetes patients with chronic limb-threatening ischemia: comparison of autologous bone marrow mononuclear cells versus allogenic Wharton jelly-derived mesenchymal stem cells |
Heart & Circulation; Other Areas of MSC Research; Cell Sources & Treatment Comparisons |
Clinical |
Early-Phase / Non-randomized Trial |
Arango-Rodríguez ML |
2023 |
37626416 ↗ |
| Results and insights from a phase I clinical trial of Lomecel-B for Alzheimer's disease |
Brain, Nerves & Neurological Conditions |
Clinical |
Early-Phase / Non-randomized Trial |
Brody M |
2023 |
35357079 ↗ |
| Label extension, single-arm, phase III study shows efficacy and safety of stempeucel® in patients with critical limb ischemia due to atherosclerotic peripheral arterial disease |
Heart & Circulation; Safety & Side Effects |
Clinical |
Early-Phase / Non-randomized Trial |
Gupta PK |
2023 |
37005673 ↗ |
| Intramyocardial cell-based therapy with Lomecel-B during bidirectional cavopulmonary anastomosis for hypoplastic left heart syndrome: the ELPIS phase I trial |
Heart & Circulation |
Clinical |
Early-Phase / Non-randomized Trial |
Kaushal S |
2023 |
36950450 ↗ |
| A Phase I Study of Ex Vivo Expanded Allogeneic Bone Marrow-Derived Mesenchymal Stem Cells for the Treatment of Pediatric Perianal Fistulizing Crohn's Disease |
Other Areas of MSC Research |
Clinical |
Early-Phase / Non-randomized Trial |
Lightner AL |
2023 |
37263018 ↗ |
| A Phase IB/IIA Study of Allogeneic, Bone Marrow-derived, Mesenchymal Stem Cells for the Treatment of Refractory Ileal-anal Anastomosis and Peripouch Fistulas in the Setting of Crohn's Disease of the Pouch |
Other Areas of MSC Research |
Clinical |
Early-Phase / Non-randomized Trial |
Lightner AL |
2023 |
36322714 ↗ |
| A Phase IB/IIA Study of Ex Vivo Expanded Allogeneic Bone Marrow-Derived Mesenchymal Stem Cells for the Treatment of Perianal Fistulizing Crohn's Disease |
Other Areas of MSC Research |
Clinical |
Early-Phase / Non-randomized Trial |
Lightner AL |
2023 |
36602511 ↗ |
| Intravitreal allogeneic mesenchymal stem cells: a non-randomized phase II clinical trial for acute non-arteritic optic neuropathy |
Brain, Nerves & Neurological Conditions; Other Areas of MSC Research |
Clinical |
Early-Phase / Non-randomized Trial |
Pastor JC |
2023 |
37735668 ↗ |
| A phase I study assessing the safety and tolerability of allogeneic mesenchymal stem cell infusion in adults with cystic fibrosis |
Other Areas of MSC Research; Safety & Side Effects |
Clinical |
Early-Phase / Non-randomized Trial |
Roesch EA |
2023 |
36549988 ↗ |
| Novel topical allogeneic bone-marrow-derived mesenchymal stem cell treatment of hard-to-heal diabetic foot ulcers: a proof of concept study |
Wound Healing & Skin Conditions |
Clinical |
Early-Phase / Non-randomized Trial |
Askø Andersen J |
2022 |
35765085 ↗ |
| Evaluation of the Effectiveness of Autologous Bone Marrow Mesenchymal Stem Cells in the Treatment of Chronic Low Back Pain Due to Severe Lumbar Spinal Degeneration: A 12-Month, Open-Label, Prospective Controlled Trial |
Back Pain & Disc Disease |
Clinical |
Early-Phase / Non-randomized Trial |
Atluri S |
2022 |
35322978 ↗ |
| Feasibility and safety of intranasally administered mesenchymal stromal cells after perinatal arterial ischaemic stroke in the Netherlands (PASSIoN): a first-in-human, open-label intervention study |
Brain, Nerves & Neurological Conditions; Safety & Side Effects |
Clinical |
Early-Phase / Non-randomized Trial |
Baak LM |
2022 |
35568047 ↗ |
| Safety and tolerability of bone marrow-derived mesenchymal stem cells in lupus animal models and a phase I clinical trial in humans |
Autoimmune & Inflammatory Conditions; Safety & Side Effects |
Clinical |
Early-Phase / Non-randomized Trial |
Chun S |
2022 |
35802867 ↗ |
| A phase IB/IIA study of remestemcel-L, an allogeneic bone marrow-derived mesenchymal stem cell product, for the treatment of medically refractory ulcerative colitis: an interim analysis |
Other Areas of MSC Research |
Clinical |
Early-Phase / Non-randomized Trial |
Lightner AL |
2022 |
35767384 ↗ |
| Remestemcel-L allogeneic bone marrow-derived mesenchymal stem cell product to treat medically refractory Crohn's colitis: preliminary phase IB/IIA study |
Other Areas of MSC Research |
Clinical |
Early-Phase / Non-randomized Trial |
Lightner AL |
2022 |
35714218 ↗ |
| The effect of mesenchymal stem cells improves the healing of burn wounds: a phase 1 dose-escalation clinical trial |
Wound Healing & Skin Conditions |
Clinical |
Early-Phase / Non-randomized Trial |
Schulman CI |
2022 |
35781931 ↗ |
| Safety of autologous freshly expanded mesenchymal stromal cells for the treatment of graft-versus-host disease |
Transplant & Blood Disorders; Safety & Side Effects; Cell Quality, Manufacturing & Delivery |
Clinical |
Early-Phase / Non-randomized Trial |
Stenger E |
2022 |
36189324 ↗ |
| Mesenchymal Stem Cell Injection in Crohn's Disease Strictures: A Phase I-II Clinical Study |
Other Areas of MSC Research |
Clinical |
Early-Phase / Non-randomized Trial |
Vieujean S |
2022 |
34473270 ↗ |
| Safety and Effectiveness of Cell Therapy in Neurodegenerative Diseases: Take-Home Messages From a Pilot Feasibility Phase I Study of Progressive Supranuclear Palsy |
Brain, Nerves & Neurological Conditions; Safety & Side Effects |
Clinical |
Early-Phase / Non-randomized Trial |
Giordano R |
2021 |
34712113 ↗ |
| Phase I clinical trial of intra-bone marrow cotransplantation of mesenchymal stem cells in cord blood transplantation |
Transplant & Blood Disorders |
Clinical |
Early-Phase / Non-randomized Trial |
Goto T |
2021 |
33314650 ↗ |
| Percutaneous administration of allogeneic bone-forming cells for the treatment of delayed unions of fractures: a pilot study |
Bone Healing & Osteonecrosis |
Clinical |
Early-Phase / Non-randomized Trial |
Jayankura M |
2021 |
34174963 ↗ |
| Safety and feasibility of subconjunctival injection of mesenchymal stem cells for acute severe ocular burns: A single-arm study |
Wound Healing & Skin Conditions; Other Areas of MSC Research; Safety & Side Effects |
Clinical |
Early-Phase / Non-randomized Trial |
Liang L |
2021 |
34333155 ↗ |
| Allogeneic Bone Marrow-Derived Mesenchymal Stem Cell Safety in Idiopathic Parkinson's Disease |
Brain, Nerves & Neurological Conditions; Safety & Side Effects |
Clinical |
Early-Phase / Non-randomized Trial |
Schiess M |
2021 |
33772873 ↗ |
| Long-term efficacy and safety of intravenous injection of clonal mesenchymal stem cells derived from bone marrow in five adults with moderate to severe atopic dermatitis |
Wound Healing & Skin Conditions; Safety & Side Effects |
Clinical |
Early-Phase / Non-randomized Trial |
Shin HT |
2021 |
33990997 ↗ |
| Efficacy and Safety of Bone Marrow-Derived Mesenchymal Stem Cells for Chronic Antibody-Mediated Rejection After Kidney Transplantation- A Single-Arm, Two-Dosing-Regimen, Phase I/II Study |
Transplant & Blood Disorders; Safety & Side Effects |
Clinical |
Early-Phase / Non-randomized Trial |
Wei Y |
2021 |
34248942 ↗ |
| First-in-human high-cumulative-dose stem cell therapy in idiopathic pulmonary fibrosis with rapid lung function decline |
Other Areas of MSC Research |
Clinical |
Early-Phase / Non-randomized Trial |
Averyanov A |
2020 |
31613055 ↗ |
| Treatment of chronic GvHD with mesenchymal stromal cells induces durable responses: A phase II study |
Transplant & Blood Disorders |
Clinical |
Early-Phase / Non-randomized Trial |
Boberg E |
2020 |
32573983 ↗ |
| [Efficacy of BMMSCs on aGVHD and Its Correlation with SerumInflammatory Cytokines in Pediatric Patients with Severe Refractory Acute Graft-Versus-Host Disease] |
Transplant & Blood Disorders; How MSCs Work |
Clinical |
Early-Phase / Non-randomized Trial |
Guo SY |
2020 |
32027286 ↗ |
| A Phase 3, Single-Arm, Prospective Study of Remestemcel-L, Ex Vivo Culture-Expanded Adult Human Mesenchymal Stromal Cells for the Treatment of Pediatric Patients Who Failed to Respond to Steroid Treatment for Acute Graft-versus-Host Disease |
Transplant & Blood Disorders |
Clinical |
Early-Phase / Non-randomized Trial |
Kurtzberg J |
2020 |
32018062 ↗ |
| Phase I/II open-label trial of intravenous allogeneic mesenchymal stromal cell therapy in adults with recessive dystrophic epidermolysis bullosa |
Wound Healing & Skin Conditions |
Clinical |
Early-Phase / Non-randomized Trial |
Rashidghamat E |
2020 |
31786163 ↗ |
| Exosomes Derived from Bone Marrow Mesenchymal Stem Cells as Treatment for Severe COVID-19 |
Other Areas of MSC Research; Cell Sources & Treatment Comparisons |
Clinical |
Early-Phase / Non-randomized Trial |
Sengupta V |
2020 |
32380908 ↗ |
| Repeat Administration of Bone Marrow-Derived Mesenchymal Stem Cells for Treatment of Amyotrophic Lateral Sclerosis |
Brain, Nerves & Neurological Conditions; Cell Quality, Manufacturing & Delivery |
Clinical |
Early-Phase / Non-randomized Trial |
Siwek T |
2020 |
33301428 ↗ |
| A Phase I Study to Evaluate Two Doses of Wharton's Jelly-Derived Mesenchymal Stromal Cells for the Treatment of De Novo High-Risk or Steroid-Refractory Acute Graft Versus Host Disease |
Transplant & Blood Disorders; Cell Quality, Manufacturing & Delivery |
Clinical |
Early-Phase / Non-randomized Trial |
Soder RP |
2020 |
32740891 ↗ |
| A proof-of-concept clinical trial using mesenchymal stem cells for the treatment of corneal epithelial stem cell deficiency |
Other Areas of MSC Research |
Clinical |
Early-Phase / Non-randomized Trial |
Calonge M |
2019 |
30578758 ↗ |
| Bone marrow transplant with post-transplant cyclophosphamide for recessive dystrophic epidermolysis bullosa expands the related donor pool and permits tolerance of nonhaematopoietic cellular grafts |
Transplant & Blood Disorders; Wound Healing & Skin Conditions |
Clinical |
Early-Phase / Non-randomized Trial |
Ebens CL |
2019 |
30843184 ↗ |
| Infusion of third-party mesenchymal stromal cells after kidney transplantation: a phase I-II, open-label, clinical study |
Transplant & Blood Disorders |
Clinical |
Early-Phase / Non-randomized Trial |
Erpicum P |
2019 |
30528263 ↗ |
| Safety and Feasibility of Repeated Intrathecal Allogeneic Bone Marrow-Derived Mesenchymal Stromal Cells in Patients with Neurological Diseases |
Brain, Nerves & Neurological Conditions; Safety & Side Effects; Cell Quality, Manufacturing & Delivery |
Clinical |
Early-Phase / Non-randomized Trial |
Pan K |
2019 |
31428161 ↗ |
| Effects of Mesenchymal Stem Cell Treatment on Systemic Cytokine Levels in a Phase 1 Dose Escalation Safety Trial of Septic Shock Patients |
Other Areas of MSC Research; Safety & Side Effects; How MSCs Work |
Clinical |
Early-Phase / Non-randomized Trial |
Schlosser K |
2019 |
30720538 ↗ |
| A Phase I Study to Assess the Safety and Cancer-Homing Ability of Allogeneic Bone Marrow-Derived Mesenchymal Stem Cells in Men with Localized Prostate Cancer |
Other Areas of MSC Research; Safety & Side Effects |
Clinical |
Early-Phase / Non-randomized Trial |
Schweizer MT |
2019 |
30735000 ↗ |
| Bone-marrow derived mesenchymal stromal cells infusion in therapy refractory juvenile idiopathic arthritis patients |
Autoimmune & Inflammatory Conditions |
Clinical |
Early-Phase / Non-randomized Trial |
Swart JF |
2019 |
31070229 ↗ |
| Cellular Immunotherapy for Septic Shock. A Phase I Clinical Trial |
Other Areas of MSC Research |
Clinical |
Early-Phase / Non-randomized Trial |
McIntyre LA |
2018 |
28960096 ↗ |
| Feasibility, Safety, and Tolerance of Mesenchymal Stem Cell Therapy for Obstructive Chronic Lung Allograft Dysfunction |
Transplant & Blood Disorders; Safety & Side Effects |
Clinical |
Early-Phase / Non-randomized Trial |
Keller CA |
2018 |
29322685 ↗ |
| Mesenchymal Stromal Cell Therapy for Chronic Lung Allograft Dysfunction: Results of a First-in-Man Study |
Transplant & Blood Disorders |
Clinical |
Early-Phase / Non-randomized Trial |
Chambers DC |
2017 |
28186707 ↗ |
| Allogeneic Human Mesenchymal Stem Cells in Patients With Idiopathic Pulmonary Fibrosis via Intravenous Delivery (AETHER): A Phase I Safety Clinical Trial |
Other Areas of MSC Research; Safety & Side Effects |
Clinical |
Early-Phase / Non-randomized Trial |
Glassberg MK |
2017 |
27890713 ↗ |
| Administration of Adult Human Bone Marrow-Derived, Cultured, Pooled, Allogeneic Mesenchymal Stromal Cells in Critical Limb Ischemia Due to Buerger's Disease: Phase II Study Report Suggests Clinical Efficacy |
Heart & Circulation |
Clinical |
Early-Phase / Non-randomized Trial |
Gupta PK |
2017 |
28297569 ↗ |
| Effects of allogeneic mesenchymal stem cell transplantation in the treatment of liver cirrhosis caused by autoimmune diseases |
Other Areas of MSC Research |
Clinical |
Early-Phase / Non-randomized Trial |
Liang J |
2017 |
28217916 ↗ |
| Cotransplantation of bone marrow-derived mesenchymal stem cells in haploidentical hematopoietic stem cell transplantation in patients with severe aplastic anemia: an interim summary for a multicenter phase II trial results |
Transplant & Blood Disorders |
Clinical |
Early-Phase / Non-randomized Trial |
Liu Z |
2017 |
28067873 ↗ |
| Allogeneic Bone Marrow-Derived Mesenchymal Stromal Cells Expanded In Vitro for Treatment of Aplastic Anemia: A Multicenter Phase II Trial |
Transplant & Blood Disorders |
Clinical |
Early-Phase / Non-randomized Trial |
Pang Y |
2017 |
28504860 ↗ |
| Allogeneic Bone-Marrow-Derived Mesenchymal stromal Cells Expanded in vitro for Treatment of Aplastic Anemia: A Multicenter Phase II Trial |
Transplant & Blood Disorders |
Clinical |
Early-Phase / Non-randomized Trial |
Pang Y |
2017 |
28960909 ↗ |
| Combined Bone Marrow-Derived Mesenchymal Stromal Cell Therapy and One-Way Endobronchial Valve Placement in Patients with Pulmonary Emphysema: A Phase I Clinical Trial |
Other Areas of MSC Research |
Clinical |
Early-Phase / Non-randomized Trial |
de Oliveira HG |
2017 |
28186686 ↗ |
| Allogeneic Mesenchymal Stem Cells Stimulate Cartilage Regeneration and Are Safe for Single-Stage Cartilage Repair in Humans upon Mixture with Recycled Autologous Chondrons |
Hip, Shoulder & Other Joints; Safety & Side Effects |
Clinical |
Early-Phase / Non-randomized Trial |
de Windt TS |
2017 |
27507787 ↗ |
| The safety of autologous and metabolically fit bone marrow mesenchymal stromal cells in medically refractory Crohn's disease – a phase 1 trial with three doses |
Other Areas of MSC Research; Safety & Side Effects |
Clinical |
Early-Phase / Non-randomized Trial |
Dhere T |
2016 |
27385373 ↗ |
| Clinical Outcomes of Transplanted Modified Bone Marrow-Derived Mesenchymal Stem Cells in Stroke: A Phase 1/2a Study |
Brain, Nerves & Neurological Conditions |
Clinical |
Early-Phase / Non-randomized Trial |
Steinberg GK |
2016 |
27256670 ↗ |
| Allogeneic clonal mesenchymal stem cell therapy for refractory graft-versus-host disease to standard treatment: a phase I study |
Transplant & Blood Disorders |
Clinical |
Early-Phase / Non-randomized Trial |
Yi HG |
2016 |
26807024 ↗ |
| Intravenous infusion of allogeneic mesenchymal stromal cells in refractory or relapsed aplastic anemia |
Transplant & Blood Disorders |
Clinical |
Early-Phase / Non-randomized Trial |
Clé DV |
2015 |
26589752 ↗ |
| Safety of allogeneic bone marrow derived mesenchymal stromal cell therapy in renal transplant recipients: the neptune study |
Transplant & Blood Disorders; Safety & Side Effects |
Clinical |
Early-Phase / Non-randomized Trial |
Reinders ME |
2015 |
26537851 ↗ |
| Insulin-secreting adipose-derived mesenchymal stromal cells with bone marrow-derived hematopoietic stem cells from autologous and allogenic sources for type 1 diabetes mellitus |
Other Areas of MSC Research |
Clinical |
Early-Phase / Non-randomized Trial |
Thakkar UG |
2015 |
25869301 ↗ |
| Mesenchymal stem (stromal) cells for treatment of ARDS: a phase 1 clinical trial |
Other Areas of MSC Research |
Clinical |
Early-Phase / Non-randomized Trial |
Wilson JG |
2015 |
25529339 ↗ |
| Allogeneic mesenchymal stem cell transplantation for lupus nephritis patients refractory to conventional therapy |
Autoimmune & Inflammatory Conditions; Other Areas of MSC Research |
Clinical |
Early-Phase / Non-randomized Trial |
Gu F |
2014 |
25119864 ↗ |
| Treatment of graft versus host disease with mesenchymal stromal cells: a phase I study on 40 adult and pediatric patients |
Transplant & Blood Disorders |
Clinical |
Early-Phase / Non-randomized Trial |
Introna M |
2014 |
24321746 ↗ |
| Unrelated donor allogeneic hematopoietic stem cell transplantation for patients with hemoglobinopathies using a reduced-intensity conditioning regimen and third-party mesenchymal stromal cells |
Transplant & Blood Disorders |
Clinical |
Early-Phase / Non-randomized Trial |
Kharbanda S |
2014 |
24370862 ↗ |
| Improvement in poor graft function after allogeneic hematopoietic stem cell transplantation upon administration of mesenchymal stem cells from third-party donors: a pilot prospective study |
Transplant & Blood Disorders |
Clinical |
Early-Phase / Non-randomized Trial |
Liu X |
2014 |
23294601 ↗ |
| Sequential third-party mesenchymal stromal cell therapy for refractory acute graft-versus-host disease |
Transplant & Blood Disorders |
Clinical |
Early-Phase / Non-randomized Trial |
Sánchez-Guijo F |
2014 |
24952358 ↗ |
| Allogeneic bone marrow mesenchymal stem cell transplantation in patients with UDCA-resistant primary biliary cirrhosis |
Other Areas of MSC Research |
Clinical |
Early-Phase / Non-randomized Trial |
Wang L |
2014 |
24835895 ↗ |
| Effects and safety of allogenic mesenchymal stem cell intravenous infusion in active ankylosing spondylitis patients who failed NSAIDs: a 20-week clinical trial |
Autoimmune & Inflammatory Conditions; Safety & Side Effects |
Clinical |
Early-Phase / Non-randomized Trial |
Wang P |
2014 |
23711393 ↗ |
| Bone marrow mesenchymal stromal cells to treat tissue damage in allogeneic stem cell transplant recipients: correlation of biological markers with clinical responses |
Transplant & Blood Disorders; How MSCs Work |
Clinical |
Early-Phase / Non-randomized Trial |
Yin F |
2014 |
24452962 ↗ |
| Comparative evaluation of efficacy of stem cells in combination with PLA/PGA membrane versus sub-epithelial connective tissue for the treatment of multiple gingival recession defects: a clinical study |
Other Areas of MSC Research; Cell Quality, Manufacturing & Delivery |
Clinical |
Early-Phase / Non-randomized Trial |
Zanwar K |
2014 |
25942341 ↗ |
| Cotransplantation of bone marrow mononuclear cells and umbilical cord mesenchymal stem cells in avascular necrosis of the femoral head |
Hip, Shoulder & Other Joints; Bone Healing & Osteonecrosis |
Clinical |
Early-Phase / Non-randomized Trial |
Cai J |
2014 |
24507042 ↗ |
| Unrelated allogeneic bone marrow-derived mesenchymal stem cells for steroid-refractory acute graft-versus-host disease: a phase I/II study |
Transplant & Blood Disorders |
Clinical |
Early-Phase / Non-randomized Trial |
Muroi K |
2013 |
23860964 ↗ |
| Autologous bone marrow-derived mesenchymal stromal cells for the treatment of allograft rejection after renal transplantation: results of a phase I study |
Transplant & Blood Disorders |
Clinical |
Early-Phase / Non-randomized Trial |
Reinders ME |
2013 |
23349326 ↗ |
| Mesenchymal stromal cell therapy for steroid-refractory acute and chronic graft versus host disease: a phase 1 study |
Transplant & Blood Disorders |
Clinical |
Early-Phase / Non-randomized Trial |
Herrmann R |
2012 |
22183779 ↗ |
| Multipotent Mesenchymal Stromal Cells for the Prophylaxis of Acute Graft-versus-Host Disease-A Phase II Study |
Transplant & Blood Disorders |
Clinical |
Early-Phase / Non-randomized Trial |
Kuzmina LA |
2012 |
22242033 ↗ |
| Co-infusion of ex vivo-expanded, parental MSCs prevents life-threatening acute GVHD, but does not reduce the risk of graft failure in pediatric patients undergoing allogeneic umbilical cord blood transplantation |
Transplant & Blood Disorders |
Clinical |
Early-Phase / Non-randomized Trial |
Bernardo ME |
2011 |
20400983 ↗ |
| [Transfusion of mesenchymal stem cells combined with haploidentical HSCT improves hematopoietic microenvironment] |
Transplant & Blood Disorders |
Clinical |
Early-Phase / Non-randomized Trial |
Hou RQ |
2010 |
20137138 ↗ |
| [Use of allogeneic mesenchymal stem cells in the treatment of intestinal inflammatory diseases] |
Other Areas of MSC Research |
Clinical |
Early-Phase / Non-randomized Trial |
Lazebnik LB |
2010 |
20387674 ↗ |
| Cotransplantation of HLA-identical mesenchymal stem cells and hematopoietic stem cells in Chinese patients with hematologic diseases |
Transplant & Blood Disorders |
Clinical |
Early-Phase / Non-randomized Trial |
Zhang X |
2010 |
19656235 ↗ |
| Adult human mesenchymal stem cells added to corticosteroid therapy for the treatment of acute graft-versus-host disease |
Transplant & Blood Disorders |
Clinical |
Early-Phase / Non-randomized Trial |
Kebriaei P |
2009 |
19539211 ↗ |
| Mesenchymal stem cell transplantation reverses multiorgan dysfunction in systemic lupus erythematosus mice and humans |
Autoimmune & Inflammatory Conditions |
Clinical |
Early-Phase / Non-randomized Trial |
Sun L |
2009 |
19489103 ↗ |
| Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study |
Transplant & Blood Disorders |
Clinical |
Early-Phase / Non-randomized Trial |
Le Blanc K |
2008 |
18468541 ↗ |
| Ex vivo expansion and in vivo infusion of bone marrow-derived Flk-1+CD31-CD34- mesenchymal stem cells: feasibility and safety from monkey to human |
Safety & Side Effects; Cell Quality, Manufacturing & Delivery |
Clinical |
Early-Phase / Non-randomized Trial |
Liu L |
2006 |
16846373 ↗ |
| Short-term zoledronic acid treatment increases bone mineral density and marrow clonogenic fibroblast progenitors after allogeneic stem cell transplantation |
Bone Healing & Osteonecrosis |
Clinical |
Early-Phase / Non-randomized Trial |
Tauchmanovà L |
2005 |
15546907 ↗ |
| Cotransplantation of HLA-identical sibling culture-expanded mesenchymal stem cells and hematopoietic stem cells in hematologic malignancy patients |
Transplant & Blood Disorders |
Clinical |
Early-Phase / Non-randomized Trial |
Lazarus HM |
2005 |
15846293 ↗ |
| Replacement of recipient stromal/mesenchymal cells after bone marrow transplantation using bone fragments and cultured osteoblast-like cells |
Transplant & Blood Disorders |
Clinical |
Early-Phase / Non-randomized Trial |
Cahill RA |
2004 |
15389437 ↗ |
| Allogeneic mesenchymal stem cell infusion for treatment of metachromatic leukodystrophy (MLD) and Hurler syndrome (MPS-IH) |
Brain, Nerves & Neurological Conditions |
Clinical |
Early-Phase / Non-randomized Trial |
Koç ON |
2002 |
12203137 ↗ |
| Healing of Perforating Inflammatory Root Resorption by Allogeneic Bone Marrow Mesenchymal Stromal Cells Transplantation: A Case Report |
Other Areas of MSC Research |
Clinical |
Real-World / Case Series / Case Report |
Gomez-Sosa JF |
2026 |
41812761 ↗ |
| Topical MSC-Derived Extracellular Vesicles Accelerate Healing of Second-Degree Burns: A Case Report |
Wound Healing & Skin Conditions; Cell Sources & Treatment Comparisons |
Clinical |
Real-World / Case Series / Case Report |
Schulman CI |
2026 |
42623276 ↗ |
| Mesenchymal stem cell therapy as adjunctive treatment in pediatric patients with severe acquired brain injury: a single-center retrospective case series |
Brain, Nerves & Neurological Conditions |
Clinical |
Real-World / Case Series / Case Report |
Uçmak H |
2026 |
42523973 ↗ |
| Treatment of Severe Acute Graft-Versus-Host Disease Refractory to Multiple Lines of Therapy: Real-World Data from 317 Adults Treated with the Multiple-Donor Bone Marrow-Derived Mesenchymal Stromal Cell Preparation Tomostrocel |
Transplant & Blood Disorders |
Clinical |
Real-World / Case Series / Case Report |
Verbeek M |
2026 |
42731730 ↗ |
| The Optimal Adjuvant Reinfusion Strategy for Aplastic Anemia: Umbilical Cord Blood or Mesenchymal Stem Cells? A Single-Center Retrospective Study |
Transplant & Blood Disorders |
Clinical |
Real-World / Case Series / Case Report |
Tan Z |
2025 |
40915607 ↗ |
| Long-term effectiveness of allogeneic bone marrow-derived mesenchymal stromal cell therapy for complex perianal and rectovaginal fistulas in Crohn's disease: a retrospective case series |
Other Areas of MSC Research |
Clinical |
Real-World / Case Series / Case Report |
Husman J |
2025 |
40759457 ↗ |
| Long-Term Follow-Up After the Application of Mesenchymal Stromal Cells in Children and Adolescents with Steroid-Refractory Graft-Versus-Host Disease |
Transplant & Blood Disorders |
Clinical |
Real-World / Case Series / Case Report |
Döring M |
2021 |
33446053 ↗ |
| Phase IV postmarketing surveillance study shows continued efficacy and safety of Stempeucel in patients with critical limb ischemia due to Buerger's disease |
Heart & Circulation; Safety & Side Effects |
Clinical |
Real-World / Case Series / Case Report |
Gupta PK |
2021 |
34519179 ↗ |
| Human Allogeneic Bone Marrow-Derived Mesenchymal Stem Cell Therapy for Cerebellar Ataxia: A Case Report |
Brain, Nerves & Neurological Conditions |
Clinical |
Real-World / Case Series / Case Report |
Ko PW |
2021 |
33915966 ↗ |
| Comparative Effectiveness of Remestemcel-L-rknd versus Ruxolitinib in Pediatric Patients with Steroid-Refractory Acute Graft-Versus-Host Disease using Simulated Treatment Comparisons |
Transplant & Blood Disorders |
Clinical |
Real-World / Case Series / Case Report |
Tremblay G |
2021 |
33768123 ↗ |
| Long-term Evaluation of Allogeneic Bone Marrow-derived Mesenchymal Stromal Cell Therapy for Crohn's Disease Perianal Fistulas |
Other Areas of MSC Research |
Clinical |
Real-World / Case Series / Case Report |
Barnhoorn MC |
2020 |
31197361 ↗ |
| Beneficial Effect of Systemic Allogeneic Adipose Derived Mesenchymal Cells on the Clinical, Inflammatory and Immunologic Status of a Patient With Recessive Dystrophic Epidermolysis Bullosa: A Case Report |
Wound Healing & Skin Conditions; How MSCs Work |
Clinical |
Real-World / Case Series / Case Report |
Maseda R |
2020 |
33324660 ↗ |
| The Effect of Transendocardial Stem Cell Injection on Erectile Function in Men With Cardiomyopathy: Results From the TRIDENT, POSEIDON, and TAC-HFT Trials |
Heart & Circulation |
Clinical |
Real-World / Case Series / Case Report |
Ory J |
2020 |
32059936 ↗ |
| Allogeneic mesenchymal stromal cells: Novel therapeutic option for mutated FLNA-associated respiratory failure in the pediatric setting |
Other Areas of MSC Research |
Clinical |
Real-World / Case Series / Case Report |
Pelizzo G |
2020 |
31468740 ↗ |
| Effects of Micronized Cartilage Matrix on Cartilage Repair in Osteochondral Lesions of the Talus |
Hip, Shoulder & Other Joints; Cell Quality, Manufacturing & Delivery |
Clinical |
Real-World / Case Series / Case Report |
Shieh AK |
2020 |
30156865 ↗ |
| Individual Tissue-Engineered Bone in Repairing Bone Defects: A 10-Year Follow-Up Study |
Bone Healing & Osteonecrosis; Cell Quality, Manufacturing & Delivery |
Clinical |
Real-World / Case Series / Case Report |
Yang P |
2020 |
32027222 ↗ |
| A panel of 4 biomarkers for the early diagnosis and therapeutic efficacy of aGVHD |
Transplant & Blood Disorders |
Clinical |
Real-World / Case Series / Case Report |
Li X |
2019 |
31434801 ↗ |
| Sequential intravenous allogeneic mesenchymal stromal cells as a potential treatment for thromboangiitis obliterans (Buerger's disease) |
Heart & Circulation |
Clinical |
Real-World / Case Series / Case Report |
Martin-Rufino JD |
2018 |
29848379 ↗ |
| Placenta-Derived Decidua Stromal Cells for Treatment of Severe Acute Graft-Versus-Host Disease |
Transplant & Blood Disorders; Cell Sources & Treatment Comparisons |
Clinical |
Real-World / Case Series / Case Report |
Ringden O |
2018 |
29533533 ↗ |
| Influence of HLA Matching on the Efficacy of Allogeneic Mesenchymal Stromal Cell Therapies for Osteoarthritis and Degenerative Disc Disease |
Back Pain & Disc Disease; Hip, Shoulder & Other Joints |
Clinical |
Real-World / Case Series / Case Report |
García-Sancho J |
2017 |
28894792 ↗ |
| Acute mobilization and migration of bone marrow-derived stem cells following anterior cruciate ligament rupture |
Tendon, Ligament & Muscle Injuries; Safety & Side Effects |
Clinical |
Real-World / Case Series / Case Report |
Maerz T |
2017 |
28284998 ↗ |
| Ex Vivo Expanded Allogeneic Mesenchymal Stem Cells With Bone Marrow Transplantation Improved Osteogenesis in Infants With Severe Hypophosphatasia |
Bone Healing & Osteonecrosis; Transplant & Blood Disorders |
Clinical |
Real-World / Case Series / Case Report |
Taketani T |
2015 |
25396326 ↗ |
| Immunomodulation effects of mesenchymal stromal cells on acute graft-versus-host disease after hematopoietic stem cell transplantation |
Transplant & Blood Disorders; How MSCs Work |
Clinical |
Real-World / Case Series / Case Report |
Zhao K |
2015 |
25300866 ↗ |
| Bone marrow mesenchymal stromal cells to treat complications following allogeneic stem cell transplantation |
Transplant & Blood Disorders |
Clinical |
Real-World / Case Series / Case Report |
Battiwalla M |
2014 |
24410434 ↗ |
| Supercharging irradiated allografts with mesenchymal stem cells improves acetabular bone grafting in revision arthroplasty |
Hip, Shoulder & Other Joints; Bone Healing & Osteonecrosis |
Clinical |
Real-World / Case Series / Case Report |
Hernigou P |
2014 |
24509980 ↗ |
| Translational research: The CD34+ cell is crucial for large-volume bone regeneration from the milieu of bone marrow progenitor cells in craniomandibular reconstruction |
Bone Healing & Osteonecrosis; Cell Quality, Manufacturing & Delivery |
Clinical |
Real-World / Case Series / Case Report |
Marx RE |
2014 |
24683583 ↗ |
| Analysis of results of acute graft-versus-host disease prophylaxis with donor multipotent mesenchymal stromal cells in patients with hemoblastoses after allogeneic bone marrow transplantation |
Transplant & Blood Disorders |
Clinical |
Real-World / Case Series / Case Report |
Shipounova IN |
2014 |
25716730 ↗ |
| Tissue-engineered ribs for chest wall reconstruction: a case with 12-year follow-up |
Bone Healing & Osteonecrosis; Cell Quality, Manufacturing & Delivery |
Clinical |
Real-World / Case Series / Case Report |
Xie HQ |
2014 |
25159061 ↗ |
| Allogeneic mesenchymal stem cell infusion for the stabilization of focal segmental glomerulosclerosis |
Other Areas of MSC Research |
Clinical |
Real-World / Case Series / Case Report |
Belingheri M |
2013 |
24135082 ↗ |
| Treatment of severe steroid resistant acute GVHD with mesenchymal stromal cells (MSC) |
Transplant & Blood Disorders |
Clinical |
Real-World / Case Series / Case Report |
Resnick IB |
2013 |
23997985 ↗ |
| Bone marrow aspirate and bone allograft to treat acetabular bone defects in revision total hip arthroplasty: preliminary report |
Hip, Shoulder & Other Joints; Bone Healing & Osteonecrosis |
Clinical |
Real-World / Case Series / Case Report |
Vulcano E |
2013 |
23893192 ↗ |
| Allogeneic mesenchymal stem cell transplantation in severe and refractory systemic lupus erythematosus: 4 years of experience |
Autoimmune & Inflammatory Conditions |
Clinical |
Real-World / Case Series / Case Report |
Wang D |
2013 |
24388428 ↗ |
| Treatment of severe post-traumatic bone defects with autologous stem cells loaded on allogeneic scaffolds |
Bone Healing & Osteonecrosis; Cell Quality, Manufacturing & Delivery |
Clinical |
Real-World / Case Series / Case Report |
Vulcano E |
2012 |
23065806 ↗ |
| Efficacy and safety of ex vivo cultured adult human mesenchymal stem cells (Prochymal™) in pediatric patients with severe refractory acute graft-versus-host disease in a compassionate use study |
Transplant & Blood Disorders; Safety & Side Effects |
Clinical |
Real-World / Case Series / Case Report |
Prasad VK |
2011 |
20457269 ↗ |
| [Allogeneic mesenchymal stromal cells in patients with ulcerative colitis: two years of observation] |
Other Areas of MSC Research |
Clinical |
Real-World / Case Series / Case Report |
Lazebnik LB |
2010 |
21485508 ↗ |
| [Pharmacoeconomic benefits of patients with ulcerative colitis treatment with help of mesenchymal stem cells] |
Other Areas of MSC Research |
Clinical |
Real-World / Case Series / Case Report |
Lazebnik LB |
2010 |
20496790 ↗ |
| Efficacy of bone marrow-derived mesenchymal stem cells in the treatment of sclerodermatous chronic graft-versus-host disease: clinical report |
Autoimmune & Inflammatory Conditions; Transplant & Blood Disorders |
Clinical |
Real-World / Case Series / Case Report |
Zhou H |
2010 |
19925878 ↗ |
| Allogenous bone grafts improved by bone marrow stem cells and platelet growth factors: clinical case reports |
Bone Healing & Osteonecrosis |
Clinical |
Real-World / Case Series / Case Report |
Filho Cerruti H |
2007 |
17437494 ↗ |
| First experience of the use bone marrow mesenchymal stem cells for the treatment of a patient with deep skin burns |
Wound Healing & Skin Conditions |
Clinical |
Real-World / Case Series / Case Report |
Rasulov MF |
2005 |
16142297 ↗ |
| Safety and preliminary efficacy of allogeneic bone marrow-derived mesenchymal stromal cells (BMSC) for painful lumbar facet arthropathy: study protocol for a randomised, double-blinded, placebo-controlled, crossover phase II clinical trial |
Back Pain & Disc Disease; Safety & Side Effects |
Clinical |
Trial Protocol |
Yan D |
2026 |
42476734 ↗ |
| Clinical Development Programme of the Innovative Mesenchymal Stromal Cell Product MSC-FFM/MC0518 for Steroid-Refractory Acute Graft-Versus-Host Disease: Design of 2 Randomised Controlled Trials in Adult and Paediatric Patients |
Transplant & Blood Disorders; Other Areas of MSC Research |
Clinical |
Trial Protocol |
Zeiser R |
2026 |
41858687 ↗ |
| Protocol for treating lumbar spinal canal stenosis with a combination of ultrapurified, allogenic bone marrow-derived mesenchymal stem cells and in situ-forming gel: a multicentre, prospective, double-blind randomised controlled trial |
Back Pain & Disc Disease |
Clinical |
Trial Protocol |
Sudo H |
2023 |
36731929 ↗ |
| MesenchymAl stromal cells for Traumatic bRain Injury (MATRIx): a study protocol for a multicenter, double-blind, randomised, placebo-controlled phase II trial |
Brain, Nerves & Neurological Conditions |
Clinical |
Trial Protocol |
Zanier ER |
2023 |
37620640 ↗ |
| The Design and Rationale of a Phase 2b, Randomized, Double-Blinded, and Placebo-Controlled Trial to Evaluate the Safety and Efficacy of Lomecel-B in Older Adults with Frailty |
Other Areas of MSC Research; Safety & Side Effects |
Clinical |
Trial Protocol |
Yousefi K |
2022 |
35441200 ↗ |
| Intrathecal Injection of Allogenic Bone Marrow-Derived Mesenchymal Stromal Cells in Treatment of Patients with Severe Ischemic Stroke: Study Protocol for a Randomized Controlled Observer-Blinded Trial |
Brain, Nerves & Neurological Conditions |
Clinical |
Trial Protocol |
Deng L |
2019 |
29796934 ↗ |
| Safety and efficacy of amnion-derived mesenchymal stem cells (AM01) in patients with steroid-refractory acute graft-versus-host disease after allogeneic haematopoietic stem cell transplantation: a study protocol for a phase I/II Japanese trial |
Transplant & Blood Disorders; Safety & Side Effects |
Clinical |
Trial Protocol |
Yamahara K |
2019 |
31289066 ↗ |
| Phase I study of cord blood transplantation with intrabone marrow injection of mesenchymal stem cells: A clinical study protocol |
Transplant & Blood Disorders |
Clinical |
Trial Protocol |
Goto T |
2018 |
29702996 ↗ |
| Rationale and design of the Clinical and Histologic Analysis of Mesenchymal Stromal Cells in AmPutations (CHAMP) trial investigating the therapeutic mechanism of mesenchymal stromal cells in the treatment of critical limb ischemia |
Heart & Circulation; How MSCs Work |
Clinical |
Trial Protocol |
Wang SK |
2018 |
29395424 ↗ |
| Rationale and design of the SAIL trial for intramuscular injection of allogeneic mesenchymal stromal cells in no-option critical limb ischemia |
Heart & Circulation |
Clinical |
Trial Protocol |
Wijnand JGJ |
2018 |
29242062 ↗ |
| Study design and rationale for ELPIS: A phase I/IIb randomized pilot study of allogeneic human mesenchymal stem cell injection in patients with hypoplastic left heart syndrome |
Heart & Circulation |
Clinical |
Trial Protocol |
Kaushal S |
2017 |
28938963 ↗ |
| Research on advanced intervention using novel bone marrOW stem cell (RAINBOW): a study protocol for a phase I, open-label, uncontrolled, dose-response trial of autologous bone marrow stromal cell transplantation in patients with acute ischemic stroke |
Brain, Nerves & Neurological Conditions; Cell Quality, Manufacturing & Delivery |
Clinical |
Trial Protocol |
Shichinohe H |
2017 |
28886699 ↗ |
| Rationale and design of the Percutaneous Stem Cell Injection Delivery Effects on Neomyogenesis in Dilated Cardiomyopathy (the POSEIDON-DCM study): a phase I/II, randomized pilot study of the comparative safety and efficacy of transendocardial injection of autologous mesenchymal stem cell vs. allogeneic mesenchymal stem cells in patients with non-ischemic dilated cardiomyopathy |
Heart & Circulation; Safety & Side Effects |
Clinical |
Trial Protocol |
Mushtaq M |
2014 |
25354998 ↗ |
| Expert Opinion on Allogeneic Bone Marrow-Derived Mesenchymal Stem Cell (BMMSC) Therapy for Knee Osteoarthritis: Clinical Insights, Efficacy, and Safety |
Knee Arthritis; Safety & Side Effects |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Londhe SB |
2026 |
42220756 ↗ |
| Bridging the Gap Between Regulatory Approval and Patient Access: The Case for Insurance Coverage of Approved Allogeneic Stem Cell Therapy in Knee Osteoarthritis |
Knee Arthritis; Other Areas of MSC Research |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Agarwal AK |
2026 |
42761145 ↗ |
| Mesenchymal stem cell therapy for diabetes: clinical evidence, emerging strategies, and future perspectives |
Other Areas of MSC Research |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Jhuang HY |
2026 |
42612969 ↗ |
| Clinical trial landscape of cell therapy for spinal cord injury: from integrated practices to future developments |
Brain, Nerves & Neurological Conditions; Other Areas of MSC Research |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Kang J |
2026 |
42477724 ↗ |
| Therapeutic Efficacy of Mesenchymal Stem Cells (MSCs) on Alzheimer's Disease: Review of Clinical Results |
Brain, Nerves & Neurological Conditions |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Kim AL |
2026 |
41533329 ↗ |
| Stem Cell Therapy as a Regenerative Strategy in Hereditary Pancreatitis Postpancreatectomy |
Other Areas of MSC Research |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Kuppa P |
2026 |
41574859 ↗ |
| Mesenchymal stem cells for recurrent miscarriage |
Other Areas of MSC Research |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Ramos FS |
2026 |
42032691 ↗ |
| A Narrative Review on Manufacturing Methods Employed in the Production of Mesenchymal Stromal Cells for Knee Osteoarthritis Therapy |
Knee Arthritis; Cell Quality, Manufacturing & Delivery |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Aabling RR |
2025 |
40002922 ↗ |
| Hierarchical therapeutic potential in the mesenchymal stem cell landscape |
Other Areas of MSC Research |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Pearl JR |
2025 |
41398594 ↗ |
| Advances in Stem Cell Therapy for Diabetic Foot Ulcers |
Wound Healing & Skin Conditions |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Wang B |
2025 |
41185855 ↗ |
| Placenta-Derived Decidua Stromal Cells: A New Frontier in the Therapy of Acute Graft-Versus-Host Disease |
Transplant & Blood Disorders; Cell Sources & Treatment Comparisons |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Ringdén O |
2024 |
38204331 ↗ |
| Mesenchymal Stromal Cells: New Generation Treatment of Inflammatory Bowel Disease |
Other Areas of MSC Research |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Wei S |
2024 |
38800593 ↗ |
| Cell therapy in patients with heart failure: a comprehensive review and emerging concepts |
Heart & Circulation |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Bolli R |
2022 |
33871588 ↗ |
| Recent Advancements in Poor Graft Function Following Hematopoietic Stem Cell Transplantation |
Transplant & Blood Disorders |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Man Y |
2022 |
35720412 ↗ |
| The promising role of autologous and allogeneic mesenchymal stromal cells in managing knee osteoarthritis. What is beyond Mesenchymal stromal cells? |
Knee Arthritis |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Pandey V |
2022 |
35242531 ↗ |
| Method Categorization of Stem Cell Therapy for Degenerative Osteoarthritis of the Knee: A Review |
Knee Arthritis |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Lee JS |
2021 |
34948119 ↗ |
| An Update for Mesenchymal Stem Cell Therapy in Lupus Nephritis |
Autoimmune & Inflammatory Conditions; Other Areas of MSC Research |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Li W |
2021 |
33824866 ↗ |
| Adult stem cells in endometrial regeneration: Molecular insights and clinical applications |
Other Areas of MSC Research |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Lv Q |
2021 |
34014590 ↗ |
| Treatment of Steroid-Refractory Acute Graft-Versus-Host Disease Using Commercial Mesenchymal Stem Cell Products |
Transplant & Blood Disorders |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Murata M |
2021 |
34489977 ↗ |
| Accentuating the sources of mesenchymal stem cells as cellular therapy for osteoarthritis knees-a panoramic review |
Knee Arthritis; Cell Sources & Treatment Comparisons |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Muthu S |
2021 |
34386542 ↗ |
| Review of the Latest Methods of Epidermolysis Bullosa and Other Chronic Wounds Treatment Including BIOOPA Dressing |
Wound Healing & Skin Conditions |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Nita M |
2021 |
34269966 ↗ |
| A focus on allogeneic mesenchymal stromal cells as a versatile therapeutic tool for treating multiple sclerosis |
Brain, Nerves & Neurological Conditions |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Shokati A |
2021 |
34256857 ↗ |
| Mesenchymal Stem Cells in Treatment of Spinal Cord Injury and Amyotrophic Lateral Sclerosis |
Brain, Nerves & Neurological Conditions |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Sykova E |
2021 |
34295897 ↗ |
| Therapeutic mechanisms of mesenchymal stem cells in acute respiratory distress syndrome reveal potentials for Covid-19 treatment |
Other Areas of MSC Research; How MSCs Work |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Wang W |
2021 |
33971907 ↗ |
| Mesenchymal stromal cell products for intra-articular knee injections for conservative management of osteoarthritis |
Knee Arthritis |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Andia I |
2021 |
33680097 ↗ |
| Mesenchymal Stem/Stromal Cells Therapy for Sepsis and Acute Respiratory Distress Syndrome |
Other Areas of MSC Research |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Byrnes D |
2021 |
32767301 ↗ |
| Local Treatment of Burns with Cell-Based Therapies Tested in Clinical Studies |
Wound Healing & Skin Conditions |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Domaszewska-Szostek AP |
2021 |
33494318 ↗ |
| Mesenchymal stromal cells for systemic sclerosis treatment |
Autoimmune & Inflammatory Conditions |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Farge D |
2021 |
33476823 ↗ |
| Cell therapy for cartilage repair |
Hip, Shoulder & Other Joints |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Hulme CH |
2021 |
34423830 ↗ |
| Mesenchymal Stromal Cells for the Treatment of Graft Versus Host Disease |
Transplant & Blood Disorders |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Kelly K |
2021 |
34764962 ↗ |
| Potential Use of Mesenchymal Multipotent Cells for Hemopoietic Stem Cell Transplantation: Pro and Contra |
How MSCs Work |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Kiselevskiy M |
2021 |
33560076 ↗ |
| Cell Therapy for Liver Disease: From Promise to Reality |
Other Areas of MSC Research |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Khan S |
2020 |
33764490 ↗ |
| Is Stem Cell Therapy the New Savior for Cerebral Palsy Patients? A Review |
Brain, Nerves & Neurological Conditions |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Vankeshwaram V |
2020 |
33042660 ↗ |
| The Potential Use of Mesenchymal Stem Cells and Their Derived Exosomes as Immunomodulatory Agents for COVID-19 Patients |
Other Areas of MSC Research; How MSCs Work; Cell Sources & Treatment Comparisons |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Alzahrani FA |
2020 |
33014070 ↗ |
| Clinical Application of Bone Marrow Mesenchymal Stem/Stromal Cells to Repair Skeletal Tissue |
Other Areas of MSC Research |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Arthur A |
2020 |
33371306 ↗ |
| MSC-Derived Extracellular Vesicles: New Emergency Treatment to Limit the Development of Radiation-Induced Hematopoietic Syndrome? |
Transplant & Blood Disorders; Cell Sources & Treatment Comparisons |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Cavallero S |
2020 |
32384375 ↗ |
| Advances in the understanding of poor graft function following allogeneic hematopoietic stem-cell transplantation |
Transplant & Blood Disorders |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Chen J |
2020 |
32874483 ↗ |
| Células madre/estromales mesenquimales. Su potencial terapéutico en medicina [Mesenchymal stem/stromal cells. Its therapeutic potential in medicine] |
Other Areas of MSC Research |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Domínguez LM |
2020 |
33254115 ↗ |
| Mesenchymal stromal cell and bone marrow concentrate therapies for musculoskeletal indications: a concise review of current literature |
Other Areas of MSC Research |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Eder C |
2020 |
32451926 ↗ |
| Mesenchymal stromal cells for osteonecrosis |
Bone Healing & Osteonecrosis |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Elgaz S |
2020 |
33081809 ↗ |
| Update on mesenchymal stromal cell studies in organ transplant recipients |
Transplant & Blood Disorders |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Fiori S |
2020 |
31815791 ↗ |
| Mesenchymal stem cell-conditioned media: A novel alternative of stem cell therapy for quality wound healing |
Wound Healing & Skin Conditions; Cell Sources & Treatment Comparisons |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Joseph A |
2020 |
31960454 ↗ |
| Cartilage repair using stem cells & biomaterials: advancement from bench to bedside |
Hip, Shoulder & Other Joints; Cell Quality, Manufacturing & Delivery |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Kakkar A |
2020 |
32888123 ↗ |
| Biomaterial and stem cell-based strategies for skeletal muscle regeneration |
Tendon, Ligament & Muscle Injuries; Cell Quality, Manufacturing & Delivery |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Dunn A |
2019 |
30604468 ↗ |
| Therapeutic Potential of Mesenchymal Stem Cells in Immune-Mediated Diseases |
Other Areas of MSC Research |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Eljarrah A |
2019 |
31898783 ↗ |
| Mesenchymal stem cell-based therapy of osteoarthritis: Current knowledge and future perspectives |
Hip, Shoulder & Other Joints |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Harrell CR |
2019 |
30551490 ↗ |
| Stem cell therapy for perianal Crohn's |
Other Areas of MSC Research |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Lightner AL |
2019 |
33216484 ↗ |
| The potential use of mesenchymal stem cells for the treatment of multiple sclerosis |
Brain, Nerves & Neurological Conditions |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Mansoor SR |
2019 |
31487529 ↗ |
| Mesenchymal stem cells in myeloproliferative disorders – focus on primary myelofibrosis |
Transplant & Blood Disorders |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Selicean SE |
2019 |
30277128 ↗ |
| Mesenchymal stem cell therapies for liver cirrhosis: MSCs as "conducting cells" for improvement of liver fibrosis and regeneration |
Other Areas of MSC Research |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Tsuchiya A |
2019 |
31516638 ↗ |
| Can we remove scar and fibrosis from adult human myocardium? |
Heart & Circulation |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Vazir A |
2019 |
30203057 ↗ |
| Application of Mesenchymal Stem Cells for Therapeutic Agent Delivery in Anti-tumor Treatment |
Other Areas of MSC Research |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Chulpanova DS |
2018 |
29615915 ↗ |
| Clinical Trials of Muse Cells |
Brain, Nerves & Neurological Conditions |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Dezawa M |
2018 |
30484237 ↗ |
| [Mesenchymal stem cell therapy in hematopoietic stem cell transplantation] |
Transplant & Blood Disorders |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Goto T |
2018 |
29515075 ↗ |
| The Current State of Advanced Therapy Medicinal Products in the Czech Republic |
Other Areas of MSC Research |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Kočí Z |
2018 |
29869533 ↗ |
| [Current basic understanding and clinical application of mesenchymal stromal/stem cells] |
Other Areas of MSC Research |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Miura Y |
2018 |
30305494 ↗ |
| Mesenchymal Stem Cells in Systemic Sclerosis: Allogenic or Autologous Approaches for Therapeutic Use? |
Autoimmune & Inflammatory Conditions |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Rozier P |
2018 |
30619298 ↗ |
| Mesenchymal Stem Cell Therapy for Aging Frailty |
Other Areas of MSC Research |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Schulman IH |
2018 |
30498696 ↗ |
| Cell-Based Therapies in Vascularized Composite Allotransplantation |
Transplant & Blood Disorders |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Vyas KS |
2018 |
29945289 ↗ |
| Mesenchymal Stem Cells to Treat Crohn's Disease with Fistula |
Other Areas of MSC Research |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Zhang XM |
2017 |
28132518 ↗ |
| Mesenchymal Stem Cells Improve Healing of Diabetic Foot Ulcer |
Wound Healing & Skin Conditions |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Cao Y |
2017 |
28386568 ↗ |
| Biomaterials and Bioactive Agents in Spinal Fusion |
Back Pain & Disc Disease; Cell Quality, Manufacturing & Delivery |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Duarte RM |
2017 |
28514897 ↗ |
| Mesenchymal Stem Cell Benefits Observed in Bone Marrow Failure and Acquired Aplastic Anemia |
Transplant & Blood Disorders |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Gonzaga VF |
2017 |
29333168 ↗ |
| Intersecting Worlds of Transfusion and Transplantation Medicine: An International Symposium Organized by the Canadian Blood Services Centre for Innovation |
Other Areas of MSC Research |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Hodgkinson KM |
2017 |
28385575 ↗ |
| Remestemcel-L for the treatment of graft versus host disease |
Transplant & Blood Disorders |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Locatelli F |
2017 |
27399600 ↗ |
| Concise Review: Mesenchymal Stem Cell Therapy for Pediatric Disease: Perspectives on Success and Potential Improvements |
Other Areas of MSC Research |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Nitkin CR |
2017 |
28191766 ↗ |
| Novel and emerging therapies in the treatment of recessive dystrophic epidermolysis bullosa |
Wound Healing & Skin Conditions |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Rashidghamat E |
2017 |
28357176 ↗ |
| Mesenchymal stromal cells in renal transplantation: opportunities and challenges |
Transplant & Blood Disorders |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Casiraghi F |
2016 |
26853275 ↗ |
| Endometrial stem/progenitor cells: the first 10 years |
Other Areas of MSC Research; Cell Sources & Treatment Comparisons |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Gargett CE |
2016 |
26552890 ↗ |
| Stem Cell Considerations for the Clinician |
Other Areas of MSC Research |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Hasty KA |
2016 |
27788904 ↗ |
| Human bone marrow mesenchymal stromal/stem cells: current clinical applications and potential for hematology |
Other Areas of MSC Research |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Miura Y |
2016 |
26692196 ↗ |
| Stem Cell Therapy for Epidermolysis Bullosa-Does It Work? |
Wound Healing & Skin Conditions |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Tamai K |
2016 |
27772543 ↗ |
| Allogeneic mesenchymal precursor cells (MPCs): an innovative approach to treating advanced heart failure |
Heart & Circulation |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Westerdahl DE |
2016 |
27376188 ↗ |
| Mesenchymal stromal cells and hematopoietic stem cell transplantation |
Transplant & Blood Disorders |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Bernardo ME |
2015 |
26116911 ↗ |
| Osteonecrosis repair with bone marrow cell therapies: state of the clinical art |
Bone Healing & Osteonecrosis |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Hernigou P |
2015 |
25016964 ↗ |
| Wharton's jelly derived mesenchymal stem cells: future of regenerative medicine? Recent findings and clinical significance |
Cell Sources & Treatment Comparisons |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Kalaszczynska I |
2015 |
25861624 ↗ |
| Wharton's Jelly-Derived Mesenchymal Stromal Cells as a Promising Cellular Therapeutic Strategy for the Management of Graft-versus-Host Disease |
Transplant & Blood Disorders |
Reviews & Opinions |
Narrative Review / Expert Opinion |
McGuirk JP |
2015 |
25894816 ↗ |
| [Bone regeneration induced by stem cells–recent research and future outlook] |
Bone Healing & Osteonecrosis |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Michaeli-Geller G |
2015 |
25799790 ↗ |
| [Prophylaxis of acute graft-versus-host disease] |
Transplant & Blood Disorders |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Murata M |
2015 |
26458454 ↗ |
| Bone marrow-derived mesenchymal stem cells for the treatment of heart failure |
Heart & Circulation |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Narita T |
2015 |
24862087 ↗ |
| Translational research of adult stem cell therapy |
Other Areas of MSC Research |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Suzuki G |
2015 |
26635920 ↗ |
| Mesenchymal stromal cells in the antimicrobial host response of hematopoietic stem cell recipients with graft-versus-host disease–friends or foes? |
Transplant & Blood Disorders |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Balan A |
2014 |
24762460 ↗ |
| Mesenchymal stem cell therapies in the treatment of musculoskeletal diseases |
Other Areas of MSC Research |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Bashir J |
2014 |
24439148 ↗ |
| Clinical challenges and opportunities of mesenchymal stem cells in musculoskeletal medicine |
Other Areas of MSC Research |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Centeno CJ |
2014 |
24439149 ↗ |
| A comprehensive review on perfusion method development for bone marrow collection and stem cell transplantation |
Cell Quality, Manufacturing & Delivery |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Korrapati N |
2014 |
25312979 ↗ |
| Clinical impact of circulating CD34-positive cells on bone regeneration and healing |
Bone Healing & Osteonecrosis |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Kuroda R |
2014 |
24372338 ↗ |
| Intractable diseases treated with intra-bone marrow-bone marrow transplantation |
Transplant & Blood Disorders |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Li M |
2014 |
25364755 ↗ |
| Mesenchymal stromal cell therapy for Crohn's disease |
Other Areas of MSC Research |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Liew A |
2014 |
25531353 ↗ |
| Endometrial regenerative cells for treatment of heart failure: a new stem cell enters the clinic |
Heart & Circulation; Other Areas of MSC Research |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Bockeria L |
2013 |
23510656 ↗ |
| Mesenchymal stem cell transplantation in multiple sclerosis |
Brain, Nerves & Neurological Conditions |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Cohen JA |
2013 |
23294498 ↗ |
| The mesenchymal stromal cells dilemma–does a negative phase III trial of random donor mesenchymal stromal cells in steroid-resistant graft-versus-host disease represent a death knell or a bump in the road? |
Transplant & Blood Disorders |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Galipeau J |
2013 |
23260081 ↗ |
| Cell-based therapies in kidney disease |
Other Areas of MSC Research |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Rosenberg ME |
2013 |
25019020 ↗ |
| Mesenchymal stromal cells: a new tool against graft-versus-host disease? |
Transplant & Blood Disorders |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Baron F |
2012 |
21963621 ↗ |
| Mezenhimske maticne stanice: imunomodulatorne znacajke i klinicka primjena [Mesenchymal stem cells: immunomodulatory properties and clinical application] |
How MSCs Work |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Golemović M |
2012 |
22519252 ↗ |
| Mesenchymal stem cells for cartilage repair in osteoarthritis |
Knee Arthritis; Hip, Shoulder & Other Joints |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Gupta PK |
2012 |
22776206 ↗ |
| Application of MultiStem(®) Allogeneic Cells for Immunomodulatory Therapy: Clinical Progress and Pre-Clinical Challenges in Prophylaxis for Graft Versus Host Disease |
Transplant & Blood Disorders; How MSCs Work |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Vaes B |
2012 |
23205020 ↗ |
| Potential benefits of allogeneic bone marrow mesenchymal stem cells for wound healing |
Wound Healing & Skin Conditions |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Badiavas AR |
2011 |
21854302 ↗ |
| Tissue-regenerating, vision-restoring corneal epithelial stem cells |
Other Areas of MSC Research |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Echevarria TJ |
2011 |
21069583 ↗ |
| Potential therapeutic applications of mesenchymal stromal cells |
Other Areas of MSC Research |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Larsen S |
2011 |
21876470 ↗ |
| [Biological treatment of gastrointestinal diseases] |
Other Areas of MSC Research |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Lazebnik LB |
2011 |
21516840 ↗ |
| Cardiac repair with allogeneic mesenchymal stem cells after myocardial infarction |
Heart & Circulation |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Vassalli G |
2011 |
21607881 ↗ |
| Emerging therapeutic approaches for multipotent mesenchymal stromal cells |
Other Areas of MSC Research |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Caimi PF |
2010 |
20729733 ↗ |
| Bone marrow-derived stem cell transplantation for the treatment of insulin-dependent diabetes |
Other Areas of MSC Research |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Fotino C |
2010 |
21060973 ↗ |
| Bone marrow and umbilical cord blood human mesenchymal stem cells: state of the art |
Cell Sources & Treatment Comparisons |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Malgieri A |
2010 |
21072260 ↗ |
| Allogenic bone-marrow-derived mesenchymal stem cells transplantation as a novel therapy for systemic lupus erythematosus |
Autoimmune & Inflammatory Conditions |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Zhang H |
2010 |
20345339 ↗ |
| Marrow stromal cell transplantation in stroke and traumatic brain injury |
Brain, Nerves & Neurological Conditions |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Li Y |
2009 |
19429146 ↗ |
| Treatment of inflammatory diseases with mesenchymal stem cells |
Other Areas of MSC Research |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Newman RE |
2009 |
19530993 ↗ |
| Cell therapy approaches for lung diseases: current status |
Other Areas of MSC Research |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Sueblinvong V |
2009 |
19349209 ↗ |
| New perspectives in human stem cell therapeutic research |
Other Areas of MSC Research |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Trounson A |
2009 |
19519878 ↗ |
| Mesenchymal stem cells and cardiac repair: principles and practice |
Heart & Circulation |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Bartunek J |
2008 |
20559905 ↗ |
| Role of mesenchymal stromal cells in solid organ transplantation |
Transplant & Blood Disorders |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Hematti P |
2008 |
18656340 ↗ |
| Placental mesenchymal and cord blood stem cell therapy for dilated cardiomyopathy |
Heart & Circulation |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Ichim TE |
2008 |
18549704 ↗ |
| Immunological properties of mesenchymal stem cells and clinical implications |
How MSCs Work |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Patel SA |
2008 |
18250975 ↗ |
| Concise review: mesenchymal stromal cells: potential for cardiovascular repair |
Heart & Circulation |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Psaltis PJ |
2008 |
18599808 ↗ |
| Transplantation of mesenchymal stem cells to enhance engraftment of hematopoietic stem cells |
Transplant & Blood Disorders |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Le Blanc K |
2007 |
17541394 ↗ |
| Allogeneic haematopoietic stem cell transplantation: current status and future outlook |
Transplant & Blood Disorders |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Aschan J |
2006 |
16968691 ↗ |
| Clinical applications of stem cell therapy–the pros and cons of stem cell sources |
Cell Sources & Treatment Comparisons |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Habib NA |
2006 |
17465781 ↗ |
| Adult mesenchymal stem cells: a pluripotent population with multiple applications |
Other Areas of MSC Research |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Porada CD |
2006 |
18220880 ↗ |
| OTI-010 Osiris Therapeutics/JCR Pharmaceuticals |
Transplant & Blood Disorders; Other Areas of MSC Research |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Taupin P |
2006 |
16729725 ↗ |
| Adult stem cells in the treatment of autoimmune diseases |
Autoimmune & Inflammatory Conditions |
Reviews & Opinions |
Narrative Review / Expert Opinion |
van Laar JM |
2006 |
16777856 ↗ |
| Allogeneic hematopoietic stem cell transplantation: state of the art and new perspectives |
Transplant & Blood Disorders |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Ringdén O |
2005 |
16480452 ↗ |
| Mesenchymal stem cells and haematopoietic stem cell transplantation |
Transplant & Blood Disorders |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Bacigalupo A |
2004 |
15498711 ↗ |
| Mesenchymal stem cells: biological characteristics and potential clinical applications |
Cell Sources & Treatment Comparisons |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Kassem M |
2004 |
15671665 ↗ |
| Mesenchymal stem cells and their potential as cardiac therapeutics |
Heart & Circulation |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Pittenger MF |
2004 |
15242981 ↗ |
| Postepy w leczeniu dystrofii mieśniowej Duchenne'a [Treatment progress of Duchenne Muscular Dystrophy (DMD)] |
Tendon, Ligament & Muscle Injuries |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Smogorzewska EM |
2004 |
15557694 ↗ |
| New directions in strategies using cell therapy for heart disease |
Heart & Circulation |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Itescu S |
2003 |
12698252 ↗ |
| Mesenkymala stamceller. Basal vetenskap och framtida kliniska användningsområden [Mesenchymal stem cells. Basic science and future clinical use] |
Other Areas of MSC Research |
Reviews & Opinions |
Narrative Review / Expert Opinion |
Le Blanc K |
2002 |
11998164 ↗ |
| Biological Therapeutic Modalities for Intervertebral Disc Diseases: An Orthoregeneration Network (ON) Foundation Review |
Back Pain & Disc Disease |
Preclinical |
Narrative Review / Expert Opinion |
Mizuno S |
2024 |
37918699 ↗ |
| Navigating the tumor microenvironment: mesenchymal stem cell-mediated delivery of anticancer agents |
Other Areas of MSC Research |
Preclinical |
Narrative Review / Expert Opinion |
Waqar MA |
2024 |
38652480 ↗ |
| Function and mechanism of mesenchymal stem cells in the healing of diabetic foot wounds |
Wound Healing & Skin Conditions; How MSCs Work |
Preclinical |
Narrative Review / Expert Opinion |
Yu X |
2023 |
37008908 ↗ |
| The Role of Mesenchymal Stem Cells (MSCs) in Veterinary Medicine and Their Use in Musculoskeletal Disorders |
How MSCs Work |
Preclinical |
Narrative Review / Expert Opinion |
Prządka P |
2021 |
34439807 ↗ |
| Cell-based immunomodulatory therapy approaches for type 1 diabetes mellitus |
Other Areas of MSC Research; How MSCs Work |
Preclinical |
Narrative Review / Expert Opinion |
Black L |
2020 |
31837998 ↗ |
| Mesenchymal Stem Cells in Aplastic Anemia and Myelodysplastic Syndromes: The "Seed and Soil" Crosstalk |
Transplant & Blood Disorders; How MSCs Work |
Preclinical |
Narrative Review / Expert Opinion |
Fattizzo B |
2020 |
32751628 ↗ |
| Extracellular Vesicles After Allogeneic Hematopoietic Cell Transplantation: Emerging Role in Post-Transplant Complications |
Transplant & Blood Disorders; Cell Sources & Treatment Comparisons |
Preclinical |
Narrative Review / Expert Opinion |
Lia G |
2020 |
32265915 ↗ |
| The Potential of Mesenchymal Stem Cells to Treat Systemic Inflammation in Horses |
Other Areas of MSC Research |
Preclinical |
Narrative Review / Expert Opinion |
MacDonald ES |
2020 |
32039250 ↗ |
| Mesenchymal Stromal Cells from Fetal and Maternal Placenta Possess Key Similarities and Differences: Potential Implications for Their Applications in Regenerative Medicine |
Cell Sources & Treatment Comparisons |
Preclinical |
Narrative Review / Expert Opinion |
Papait A |
2020 |
31935836 ↗ |
| Current Status and Future Prospects of Perinatal Stem Cells |
Brain, Nerves & Neurological Conditions; Cell Sources & Treatment Comparisons |
Preclinical |
Narrative Review / Expert Opinion |
Torre P |
2020 |
33374593 ↗ |
| The regulation of normal and neoplastic hematopoiesis is dependent on microenvironmental cells |
Transplant & Blood Disorders |
Preclinical |
Narrative Review / Expert Opinion |
Kaushansky K |
2018 |
29970351 ↗ |
| Germline mutations in the bone marrow microenvironment and dysregulated hematopoiesis |
Transplant & Blood Disorders |
Preclinical |
Narrative Review / Expert Opinion |
Miller LH |
2018 |
30076950 ↗ |
| Concepts and challenges in the use of mesenchymal stem cells as a treatment for cartilage damage in the horse |
Hip, Shoulder & Other Joints |
Preclinical |
Narrative Review / Expert Opinion |
Zayed M |
2018 |
29601969 ↗ |
| Postnatal extra-embryonic tissues as a source of multiple cell types for regenerative medicine applications |
Cell Sources & Treatment Comparisons |
Preclinical |
Narrative Review / Expert Opinion |
Gubar OS |
2017 |
28967638 ↗ |
| The dichotomy of placenta-derived cells in cancer growth |
Other Areas of MSC Research; Cell Sources & Treatment Comparisons |
Preclinical |
Narrative Review / Expert Opinion |
Silini AR |
2017 |
28545651 ↗ |
| Mesenchymal stromal cells with enhanced therapeutic properties |
Cell Quality, Manufacturing & Delivery |
Preclinical |
Narrative Review / Expert Opinion |
Girdlestone J |
2016 |
28000538 ↗ |
| Concise Review: Stem Cell Trials Using Companion Animal Disease Models |
Other Areas of MSC Research |
Preclinical |
Narrative Review / Expert Opinion |
Hoffman AM |
2016 |
27066769 ↗ |
| Stem and progenitor cells: advancing bone tissue engineering |
Bone Healing & Osteonecrosis; Cell Quality, Manufacturing & Delivery |
Preclinical |
Narrative Review / Expert Opinion |
Tevlin R |
2016 |
25990836 ↗ |
| Cardiac Regenerative Medicine: The Potential of a New Generation of Stem Cells |
Heart & Circulation |
Preclinical |
Narrative Review / Expert Opinion |
Cambria E |
2016 |
27721703 ↗ |
| Stem cells and applications: a survey |
Other Areas of MSC Research |
Preclinical |
Narrative Review / Expert Opinion |
Stoltz JF |
2015 |
25538052 ↗ |
| Stem Cells and Regenerative Medicine: Myth or Reality of the 21th Century |
Other Areas of MSC Research |
Preclinical |
Narrative Review / Expert Opinion |
Stoltz JF |
2015 |
26300923 ↗ |
| Mesenchymal stem cells for regenerative therapy: optimization of cell preparation protocols |
Cell Quality, Manufacturing & Delivery |
Preclinical |
Narrative Review / Expert Opinion |
Ikebe C |
2014 |
24511552 ↗ |
| Cell sources for nucleus pulposus regeneration |
Back Pain & Disc Disease; Cell Sources & Treatment Comparisons |
Preclinical |
Narrative Review / Expert Opinion |
Kregar Velikonja N |
2014 |
24297331 ↗ |
| Hypoxic culture conditions for Mesenchymal Stromal/Stem Cells from Wharton's jelly: a critical parameter to consider in a therapeutic context |
Cell Quality, Manufacturing & Delivery |
Preclinical |
Narrative Review / Expert Opinion |
Reppel L |
2014 |
24524785 ↗ |
| Mesenchymal stem cells as a vector for the inflammatory prostate microenvironment |
Other Areas of MSC Research |
Preclinical |
Narrative Review / Expert Opinion |
Brennen WN |
2013 |
23975882 ↗ |
| [Mesenchymal stem cells and their immunological properties] |
How MSCs Work |
Preclinical |
Narrative Review / Expert Opinion |
Lisianyĭ MI |
2013 |
23957174 ↗ |
| Adipose-derived stromal cells (ASCs) |
Cell Sources & Treatment Comparisons |
Preclinical |
Narrative Review / Expert Opinion |
Bassi G |
2012 |
22818214 ↗ |
| Cell sources for cartilage repair; contribution of the mesenchymal perivascular niche |
Hip, Shoulder & Other Joints; Cell Sources & Treatment Comparisons |
Preclinical |
Narrative Review / Expert Opinion |
Diaz-Flores L Jr |
2012 |
22652871 ↗ |
| Mesenchymal stem cells in drug/gene delivery: implications for cell therapy |
Other Areas of MSC Research |
Preclinical |
Narrative Review / Expert Opinion |
Greco SJ |
2012 |
22946432 ↗ |
| Mesenchymal stem cells, sources of cells and differentiation potential |
Cell Sources & Treatment Comparisons |
Preclinical |
Narrative Review / Expert Opinion |
Khan WS |
2012 |
23550346 ↗ |
| Biologic and immunomodulatory properties of mesenchymal stromal cells derived from human pancreatic islets |
How MSCs Work; Cell Sources & Treatment Comparisons |
Preclinical |
Narrative Review / Expert Opinion |
Kim J |
2012 |
22571381 ↗ |
| Immunomodulatory activity of mesenchymal stem cells |
How MSCs Work |
Preclinical |
Narrative Review / Expert Opinion |
Kaplan JM |
2011 |
21190531 ↗ |
| Immunomodulatory properties and therapeutic application of mesenchymal stem cells |
How MSCs Work |
Preclinical |
Narrative Review / Expert Opinion |
Shi M |
2011 |
21352202 ↗ |
| New insights into mesenchymal stromal cell-mediated T-cell suppression through galectins |
How MSCs Work |
Preclinical |
Narrative Review / Expert Opinion |
Sioud M |
2011 |
21198747 ↗ |
| Human bone marrow and adipose tissue mesenchymal stem cells: a user's guide |
Cell Sources & Treatment Comparisons; Cell Quality, Manufacturing & Delivery |
Preclinical |
Narrative Review / Expert Opinion |
Mosna F |
2010 |
20486777 ↗ |
| Mesenchymal stem cells: immunobiology and role in immunomodulation and tissue regeneration |
How MSCs Work |
Preclinical |
Narrative Review / Expert Opinion |
Kode JA |
2009 |
19568970 ↗ |
| Dichotomous role of interferon-gamma in allogeneic bone marrow transplant |
Transplant & Blood Disorders; How MSCs Work |
Preclinical |
Narrative Review / Expert Opinion |
Lu Y |
2009 |
19822293 ↗ |
| Mesenchymal stem cell-based therapy: a new paradigm in regenerative medicine |
Other Areas of MSC Research |
Preclinical |
Narrative Review / Expert Opinion |
Satija NK |
2009 |
19602034 ↗ |
| Why are MSCs therapeutic? New data: new insight |
How MSCs Work |
Preclinical |
Narrative Review / Expert Opinion |
Caplan AI |
2009 |
19023885 ↗ |
| Mesenchymal stromal cells as supportive cells for hepatocytes |
Other Areas of MSC Research |
Preclinical |
Narrative Review / Expert Opinion |
Gómez-Aristizábal A |
2009 |
19584815 ↗ |
| Harnessing stem cells and dendritic cells for novel therapies |
How MSCs Work |
Preclinical |
Narrative Review / Expert Opinion |
Markowicz S |
2008 |
19172843 ↗ |
| Flexible and dynamic organization of bone marrow stromal compartment |
Cell Sources & Treatment Comparisons |
Preclinical |
Narrative Review / Expert Opinion |
Anjos-Afonso F |
2007 |
17910627 ↗ |
| Adult mesenchymal stem cells for tissue engineering versus regenerative medicine |
Cell Quality, Manufacturing & Delivery |
Preclinical |
Narrative Review / Expert Opinion |
Caplan AI |
2007 |
17620285 ↗ |
| The immune properties of mesenchymal stem cells |
How MSCs Work |
Preclinical |
Narrative Review / Expert Opinion |
Castillo M |
2007 |
23675026 ↗ |
| Modulation of immune responses by mesenchymal stem cells |
Safety & Side Effects; How MSCs Work |
Preclinical |
Narrative Review / Expert Opinion |
Fibbe WE |
2007 |
17442776 ↗ |
| Mesenchymal stromal cells: Tissue repair and immune modulation |
How MSCs Work |
Preclinical |
Narrative Review / Expert Opinion |
Le Blanc K |
2006 |
17148032 ↗ |
| Human fetal mesenchymal stem cells |
Cell Sources & Treatment Comparisons |
Preclinical |
Narrative Review / Expert Opinion |
O'Donoghue K |
2006 |
18220881 ↗ |
| Adult stem cells in bone and cartilage tissue engineering |
Hip, Shoulder & Other Joints; Cell Quality, Manufacturing & Delivery |
Preclinical |
Narrative Review / Expert Opinion |
Salgado AJ |
2006 |
18220879 ↗ |
| Mesenchymal stem cells for bone repair: preclinical studies and potential orthopedic applications |
Bone Healing & Osteonecrosis |
Preclinical |
Narrative Review / Expert Opinion |
Arinzeh TL |
2005 |
16297825 ↗ |
| Immunobiology of human mesenchymal stem cells and future use in hematopoietic stem cell transplantation |
Transplant & Blood Disorders; How MSCs Work |
Preclinical |
Narrative Review / Expert Opinion |
Le Blanc K |
2005 |
15846285 ↗ |
| Mesenchymal stem cells: cell biology and potential use in therapy |
Other Areas of MSC Research |
Preclinical |
Narrative Review / Expert Opinion |
Kassem M |
2004 |
15546474 ↗ |
| Stem cells for regenerative medicine: advances in the engineering of tissues and organs |
Other Areas of MSC Research |
Preclinical |
Narrative Review / Expert Opinion |
Ringe J |
2002 |
12435034 ↗ |
| Mesenchymal stem cells: stealth and suppression |
How MSCs Work |
Preclinical |
Narrative Review / Expert Opinion |
Devine SM |
2001 |
11777268 ↗ |
| Mesenchymal stem cells in osteobiology and applied bone regeneration |
Bone Healing & Osteonecrosis |
Preclinical |
Narrative Review / Expert Opinion |
Bruder SP |
1998 |
9917644 ↗ |
| Stem cell-derived exosomes for ischemic stroke: a conventional and network meta-analysis based on animal models |
Brain, Nerves & Neurological Conditions; Cell Sources & Treatment Comparisons |
Preclinical |
Systematic Review / Meta-analysis |
Xu K |
2024 |
39508049 ↗ |
| Therapeutic Potential of Mesenchymal Stromal Stem Cells in Rheumatoid Arthritis: a Systematic Review of In Vivo Studies |
Autoimmune & Inflammatory Conditions |
Preclinical |
Systematic Review / Meta-analysis |
Karamini A |
2020 |
31950339 ↗ |
| Timing for Intravenous Injection of Mesenchymal Stem Cells to Enhance Fracture Healing |
Bone Healing & Osteonecrosis; Cell Quality, Manufacturing & Delivery |
Preclinical |
Preclinical – Animal / Veterinary |
Kim KI |
2026 |
42646164 ↗ |
| Repair of infarcted myocardium by skeletal muscle-derived mesenchymal stromal cells delivered by a bioprinted collagen patch |
Tendon, Ligament & Muscle Injuries; Heart & Circulation; Cell Quality, Manufacturing & Delivery |
Preclinical |
Preclinical – Animal / Veterinary |
Guesdon R |
2025 |
40764930 ↗ |
| Poly(glycerol sebacate) copolymer seeded with mesenchymal stem cells and growth differentiation factor 5-loaded nanoparticles for full-thickness cartilage repair |
Hip, Shoulder & Other Joints; Cell Quality, Manufacturing & Delivery |
Preclinical |
Preclinical – Animal / Veterinary |
Mamachan M |
2025 |
40388010 ↗ |
| Effect of Allogenic Mesenchymal Stem Cell Injection on Functional Repair Outcomes Following Skeletal Muscle Laceration Injury |
Tendon, Ligament & Muscle Injuries |
Preclinical |
Preclinical – Animal / Veterinary |
Ahmad RE |
2025 |
41301902 ↗ |
| 3D Porous Polymer Scaffold-Conjugated KGF-Mimetic Peptide Promotes Functional Skin Regeneration in Chronic Diabetic Wounds |
Wound Healing & Skin Conditions; Cell Quality, Manufacturing & Delivery |
Preclinical |
Preclinical – Animal / Veterinary |
Choudhury S |
2024 |
38980153 ↗ |
| Therapeutic Effects of IL-1RA, M2 Cells, and Their Synergistic Impact on a Mouse Model of Rheumatoid Arthritis |
Autoimmune & Inflammatory Conditions |
Preclinical |
Preclinical – Animal / Veterinary |
Hashemzadeh MS |
2024 |
39206397 ↗ |
| Bone formation by human paediatric marrow stromal cells in a functional allogeneic immune system |
Bone Healing & Osteonecrosis |
Preclinical |
Preclinical – Animal / Veterinary |
Palomares Cabeza V |
2024 |
38377846 ↗ |
| Macrophage tracking with USPIO imaging and T2 mapping predicts immune rejection of transplanted stem cells |
Safety & Side Effects; How MSCs Work |
Preclinical |
Preclinical – Animal / Veterinary |
Wang W |
2024 |
39587241 ↗ |
| Optimized Allogenic Decellularized Meniscal Scaffold Modified by Collagen Affinity Stromal Cell-Derived Factor SDF1α for Meniscal Regeneration: A 6- and 12-Week Animal Study in a Rabbit Model |
Hip, Shoulder & Other Joints; Cell Quality, Manufacturing & Delivery |
Preclinical |
Preclinical – Animal / Veterinary |
Zhang T |
2024 |
38164676 ↗ |
| Cryopreserved allogeneic bone marrow mesenchymal stem cells show better osteochondral defect repair potential than adipose tissue mesenchymal stem cells |
Hip, Shoulder & Other Joints; Cell Quality, Manufacturing & Delivery |
Preclinical |
Preclinical – Animal / Veterinary |
Gugjoo MB |
2023 |
36436354 ↗ |
| Decellularized allogeneic cartilage paste with human costal cartilage and crosslinked hyaluronic acid-carboxymethyl cellulose carrier augments microfracture for improved articular cartilage repair |
Hip, Shoulder & Other Joints; Cell Quality, Manufacturing & Delivery |
Preclinical |
Preclinical – Animal / Veterinary |
Lee KW |
2023 |
37813156 ↗ |
| Experimental Correction and Treatment of Chronic Liver Failure Using Implantable Cell-Engineering Constructs of the Auxiliary Liver Based on a Bioactive Heterogeneous Biopolymer Hydrogel |
Other Areas of MSC Research; Cell Quality, Manufacturing & Delivery |
Preclinical |
Preclinical – Animal / Veterinary |
Shagidulin M |
2023 |
37367127 ↗ |
| A pilot study to demonstrate the paracrine effect of equine, adult allogenic mesenchymal stem cells in vitro, with a potential for healing of experimentally-created, equine thoracic wounds in vivo |
Wound Healing & Skin Conditions; How MSCs Work |
Preclinical |
Preclinical – Animal / Veterinary |
Caruso M |
2022 |
36452146 ↗ |
| Cryopreserved allogeneic mesenchymal stem cells enhance wound repair in full thickness skin wound model and cattle clinical teat injuries |
Wound Healing & Skin Conditions; Cell Quality, Manufacturing & Delivery |
Preclinical |
Preclinical – Animal / Veterinary |
Dar ER |
2022 |
35940080 ↗ |
| Transplantation of insulin-producing cells derived from human mesenchymal stromal/stem cells into diabetic humanized mice |
Other Areas of MSC Research |
Preclinical |
Preclinical – Animal / Veterinary |
Ghoneim MA |
2022 |
35883190 ↗ |
| Comparative evaluation of fracture healing potential of differentiated and undifferentiated guinea pig and canine bone marrow-derived mesenchymal stem cells in a guinea pig model |
Bone Healing & Osteonecrosis |
Preclinical |
Preclinical – Animal / Veterinary |
Peer BA |
2022 |
35257943 ↗ |
| Allogeneic Cell Combination Therapy Ameliorates Chronic Kidney Disease-Induced Heart Failure with Preserved Ejection Fraction |
Heart & Circulation; Other Areas of MSC Research |
Preclinical |
Preclinical – Animal / Veterinary |
Rieger AC |
2022 |
35641169 ↗ |
| Allogeneic umbilical cord-derived mesenchymal stem cells for treating critical-sized bone defects: a translational study |
Bone Healing & Osteonecrosis |
Preclinical |
Preclinical – Animal / Veterinary |
Dilogo IH |
2021 |
32804289 ↗ |
| Paradoxical Regulation of Allogeneic Bone Marrow Engraftment and Immune Privilege by Mesenchymal Cells and Adenosine |
Transplant & Blood Disorders; How MSCs Work |
Preclinical |
Preclinical – Animal / Veterinary |
Kakiuchi M |
2021 |
32961376 ↗ |
| Cell-free scaffolds functionalized with bionic cartilage acellular matrix microspheres to enhance the microfracture treatment of articular cartilage defects |
Hip, Shoulder & Other Joints; Cell Quality, Manufacturing & Delivery |
Preclinical |
Preclinical – Animal / Veterinary |
Liu J |
2021 |
33491727 ↗ |
| Comparative analysis of mouse bone marrow and adipose tissue mesenchymal stem cells for critical limb ischemia cell therapy |
Heart & Circulation; Cell Sources & Treatment Comparisons |
Preclinical |
Preclinical – Animal / Veterinary |
Nammian P |
2021 |
33436054 ↗ |
| Safety of Intraovarian Injection of Human Mesenchymal Stem Cells in a Premature Ovarian Insufficiency Mouse Model |
Other Areas of MSC Research; Safety & Side Effects |
Preclinical |
Preclinical – Animal / Veterinary |
Park HS |
2021 |
33593078 ↗ |
| Engineered mucoperiosteal scaffold for cleft palate regeneration towards the non-immunogenic transplantation |
Bone Healing & Osteonecrosis; Safety & Side Effects; Cell Quality, Manufacturing & Delivery |
Preclinical |
Preclinical – Animal / Veterinary |
Rizzo MI |
2021 |
34272436 ↗ |
| Non-clinical assessment of safety, biodistribution and tumorigenicity of human mesenchymal stromal cells |
Other Areas of MSC Research; Safety & Side Effects; Cell Quality, Manufacturing & Delivery |
Preclinical |
Preclinical – Animal / Veterinary |
Thäte C |
2021 |
34926173 ↗ |
| A partially demineralized allogeneic bone graft: in vitro osteogenic potential and preclinical evaluation in two different intramembranous bone healing models |
Bone Healing & Osteonecrosis |
Preclinical |
Preclinical – Animal / Veterinary |
Tournier P |
2021 |
33649345 ↗ |
| Allogeneic Bone Marrow Mesenchymal Stem Cell Transplantation in Tooth Extractions Sites Ameliorates the Incidence of Osteonecrotic Jaw-Like Lesions in Zoledronic Acid-Treated Rats |
Bone Healing & Osteonecrosis; Other Areas of MSC Research |
Preclinical |
Preclinical – Animal / Veterinary |
Rodríguez-Lozano FJ |
2020 |
32486396 ↗ |
| Extracellular matrix derived from allogenic decellularized bone marrow mesenchymal stem cell sheets for the reconstruction of osteochondral defects in rabbits |
Hip, Shoulder & Other Joints; Cell Quality, Manufacturing & Delivery |
Preclinical |
Preclinical – Animal / Veterinary |
Wang Z |
2020 |
33068746 ↗ |
| Allogeneic vs. autologous intra-articular mesenchymal stem cell injection within normal horses: Clinical and cytological comparisons suggest safety |
Hip, Shoulder & Other Joints; Safety & Side Effects |
Preclinical |
Preclinical – Animal / Veterinary |
Colbath AC |
2020 |
31120574 ↗ |
| Single and repeated intra-articular injections in the tarsocrural joint with allogeneic and autologous equine bone marrow-derived mesenchymal stem cells are safe, but did not reduce acute inflammation in an experimental interleukin-1β model of synovitis |
Hip, Shoulder & Other Joints; Safety & Side Effects; Cell Quality, Manufacturing & Delivery |
Preclinical |
Preclinical – Animal / Veterinary |
Colbath AC |
2020 |
31821594 ↗ |
| Cxcr6-Based Mesenchymal Stem Cell Gene Therapy Potentiates Skin Regeneration in Murine Diabetic Wounds |
Wound Healing & Skin Conditions |
Preclinical |
Preclinical – Animal / Veterinary |
Dhoke NR |
2020 |
32112713 ↗ |
| Human amniotic mesenchymal stromal cells promote bone regeneration via activating endogenous regeneration |
Bone Healing & Osteonecrosis |
Preclinical |
Preclinical – Animal / Veterinary |
Jiang F |
2020 |
32483449 ↗ |
| Effects of local injection and intravenous injection of allogeneic bone marrow mesenchymal stem cells on the structure and function of damaged anal sphincter in rats |
Other Areas of MSC Research; Cell Quality, Manufacturing & Delivery |
Preclinical |
Preclinical – Animal / Veterinary |
Li P |
2020 |
32537834 ↗ |
| In vivo cartilage regeneration in a multi-layered articular cartilage architecture mimicking scaffold |
Hip, Shoulder & Other Joints; Cell Quality, Manufacturing & Delivery |
Preclinical |
Preclinical – Animal / Veterinary |
Rajagopal K |
2020 |
33014353 ↗ |
| Intra-Articular Injection of 2 Different Dosages of Autologous and Allogeneic Bone Marrow- and Umbilical Cord-Derived Mesenchymal Stem Cells Triggers a Variable Inflammatory Response of the Fetlock Joint on 12 Sound Experimental Horses |
Hip, Shoulder & Other Joints; Safety & Side Effects; Cell Quality, Manufacturing & Delivery |
Preclinical |
Preclinical – Animal / Veterinary |
Bertoni L |
2019 |
31191689 ↗ |
| Use of Allogeneic Hypoxic Mesenchymal Stem Cells For Treating Disc Degeneration in Rabbits |
Back Pain & Disc Disease |
Preclinical |
Preclinical – Animal / Veterinary |
Chiang ER |
2019 |
31062869 ↗ |
| Transplantation of human ESC-derived mesenchymal stem cell spheroids ameliorates spontaneous osteoarthritis in rhesus macaques |
Hip, Shoulder & Other Joints; Cell Quality, Manufacturing & Delivery |
Preclinical |
Preclinical – Animal / Veterinary |
Jiang B |
2019 |
31588237 ↗ |
| Tendon-to-Bone Healing in a Rat Extra-articular Bone Tunnel Model: A Comparison of Fresh Autologous Bone Marrow and Bone Marrow-Derived Mesenchymal Stem Cells |
Bone Healing & Osteonecrosis; Tendon, Ligament & Muscle Injuries |
Preclinical |
Preclinical – Animal / Veterinary |
Lu J |
2019 |
31339739 ↗ |
| The Secretome Derived From 3D-Cultured Umbilical Cord Tissue MSCs Counteracts Manifestations Typifying Rheumatoid Arthritis |
Autoimmune & Inflammatory Conditions; Cell Sources & Treatment Comparisons; Cell Quality, Manufacturing & Delivery |
Preclinical |
Preclinical – Animal / Veterinary |
Miranda JP |
2019 |
30804924 ↗ |
| Denatured acellular dermal matrix seeded with bone marrow mesenchymal stem cells for wound healing in mice |
Wound Healing & Skin Conditions; Cell Quality, Manufacturing & Delivery |
Preclinical |
Preclinical – Animal / Veterinary |
Qi Y |
2019 |
31072713 ↗ |
| Retrospective analysis of local injection site adverse reactions associated with 230 allogenic administrations of bone marrow-derived mesenchymal stem cells in 164 horses |
Safety & Side Effects; Cell Quality, Manufacturing & Delivery |
Preclinical |
Preclinical – Animal / Veterinary |
Ursini TL |
2019 |
29992618 ↗ |
| Assessment of effectiveness and safety of repeat administration of proinflammatory primed allogeneic mesenchymal stem cells in an equine model of chemically induced osteoarthritis |
Hip, Shoulder & Other Joints; Safety & Side Effects; Cell Quality, Manufacturing & Delivery |
Preclinical |
Preclinical – Animal / Veterinary |
Barrachina L |
2018 |
30119668 ↗ |
| Placenta-derived mesenchymal stromal cells and their exosomes exert therapeutic effects in Duchenne muscular dystrophy |
Tendon, Ligament & Muscle Injuries; Cell Sources & Treatment Comparisons |
Preclinical |
Preclinical – Animal / Veterinary |
Bier A |
2018 |
29783118 ↗ |
| Inhibitory Effects of iPSC-MSCs and Their Extracellular Vesicles on the Onset of Sialadenitis in a Mouse Model of Sjögren's Syndrome |
Autoimmune & Inflammatory Conditions; Cell Sources & Treatment Comparisons |
Preclinical |
Preclinical – Animal / Veterinary |
Hai B |
2018 |
29736173 ↗ |
| Anti-inflammatory Role of Mesenchymal Stem Cells in an Acute Lung Injury Mouse Model |
Other Areas of MSC Research; How MSCs Work |
Preclinical |
Preclinical – Animal / Veterinary |
Huh JW |
2018 |
31723879 ↗ |
| Bone marrow-derived mesenchymal stem cells laden novel thermo-sensitive hydrogel for the management of severe skin wound healing |
Wound Healing & Skin Conditions; Cell Quality, Manufacturing & Delivery |
Preclinical |
Preclinical – Animal / Veterinary |
Lei Z |
2018 |
29853078 ↗ |
| In vitro MSC function is related to clinical reaction in vivo |
Safety & Side Effects |
Preclinical |
Preclinical – Animal / Veterinary |
Rowland AL |
2018 |
30409211 ↗ |
| Application of a Demineralized Cortical Bone Matrix and Bone Marrow-Derived Mesenchymal Stem Cells in a Model of Chronic Rotator Cuff Degeneration |
Tendon, Ligament & Muscle Injuries; Cell Quality, Manufacturing & Delivery |
Preclinical |
Preclinical – Animal / Veterinary |
Thangarajah T |
2018 |
28949253 ↗ |
| The effectiveness of allogeneic mesenchymal stem cells therapy for knee osteoarthritis in pigs |
Knee Arthritis |
Preclinical |
Preclinical – Animal / Veterinary |
Xia T |
2018 |
30498731 ↗ |
| Immunoselected STRO-3+ mesenchymal precursor cells reduce inflammation and improve clinical outcomes in a large animal model of monoarthritis |
Hip, Shoulder & Other Joints |
Preclinical |
Preclinical – Animal / Veterinary |
Abdalmula A |
2017 |
28173831 ↗ |
| Systemic Delivery of Bone Marrow Mesenchymal Stem Cells for In Situ Intervertebral Disc Regeneration |
Back Pain & Disc Disease; Cell Quality, Manufacturing & Delivery |
Preclinical |
Preclinical – Animal / Veterinary |
Cunha C |
2017 |
28297581 ↗ |
| Biodistribution and Immunogenicity of Allogeneic Mesenchymal Stem Cells in a Rat Model of Intraarticular Chondrocyte Xenotransplantation |
Hip, Shoulder & Other Joints; Safety & Side Effects |
Preclinical |
Preclinical – Animal / Veterinary |
Marquina M |
2017 |
29163532 ↗ |
| Human chondroprogenitors in alginate-collagen hybrid scaffolds produce stable cartilage in vivo |
Hip, Shoulder & Other Joints; Cell Quality, Manufacturing & Delivery |
Preclinical |
Preclinical – Animal / Veterinary |
Studer D |
2017 |
27373220 ↗ |
| The role of bone marrow mesenchymal stromal cell derivatives in skin wound healing in diabetic mice |
Wound Healing & Skin Conditions; Cell Sources & Treatment Comparisons |
Preclinical |
Preclinical – Animal / Veterinary |
de Mayo T |
2017 |
28594903 ↗ |
| Local delivery of allogeneic bone marrow and adipose tissue-derived mesenchymal stromal cells for cutaneous wound healing in a porcine model |
Wound Healing & Skin Conditions; Cell Sources & Treatment Comparisons; Cell Quality, Manufacturing & Delivery |
Preclinical |
Preclinical – Animal / Veterinary |
Hanson SE |
2016 |
23418160 ↗ |
| Mesenchymal Stromal Cell-Derived Extracellular Vesicles Protect the Fetal Brain After Hypoxia-Ischemia |
Brain, Nerves & Neurological Conditions; Cell Sources & Treatment Comparisons |
Preclinical |
Preclinical – Animal / Veterinary |
Ophelders DR |
2016 |
27160705 ↗ |
| Preclinical safety & toxicity evaluation of pooled, allogeneic human bone marrow-derived mesenchymal stromal cells |
Safety & Side Effects; Cell Quality, Manufacturing & Delivery |
Preclinical |
Preclinical – Animal / Veterinary |
Rengasamy M |
2016 |
28474622 ↗ |
| Effect of Allogeneic Bone Marrow-mesenchymal Stem Cells (BM-MSCs) to Accelerate Burn Healing of Rat on the Expression of Collagen Type I and Integrin α2β1 |
Wound Healing & Skin Conditions |
Preclinical |
Preclinical – Animal / Veterinary |
Revilla G |
2016 |
29023021 ↗ |
| Efficacy of allogeneic mesenchymal stem cell administration in a model of acute ischemic kidney injury in cats |
Other Areas of MSC Research |
Preclinical |
Preclinical – Animal / Veterinary |
Rosselli DD |
2016 |
27663365 ↗ |
| IMMUNOMODULATORY EFFECT OF ALLOGENEIC MESENCHYMAL STEM CELLS OF RATS |
How MSCs Work |
Preclinical |
Preclinical – Animal / Veterinary |
Trubitsyna IE |
2016 |
29889447 ↗ |
| Inflammatory response to the administration of mesenchymal stem cells in an equine experimental model: effect of autologous, and single and repeat doses of pooled allogeneic cells in healthy joints |
Hip, Shoulder & Other Joints; Safety & Side Effects; Cell Quality, Manufacturing & Delivery |
Preclinical |
Preclinical – Animal / Veterinary |
Ardanaz N |
2016 |
27029614 ↗ |
| Bone Marrow-Derived Mesenchymal Stem Cells Enhance Bacterial Clearance and Preserve Bioprosthetic Integrity in a Model of Mesh Infection |
How MSCs Work |
Preclinical |
Preclinical – Animal / Veterinary |
Criman ET |
2016 |
27482490 ↗ |
| Effect of bone marrow and adipose tissue-derived mesenchymal stem cells on the natural course of corneal scarring after penetrating injury |
Other Areas of MSC Research; Cell Sources & Treatment Comparisons |
Preclinical |
Preclinical – Animal / Veterinary |
Demirayak B |
2016 |
27567556 ↗ |
| Intra-Articular Transplantation of Allogeneic BMMSCs Rehabilitates Cartilage Injury of Antigen-Induced Arthritis |
Hip, Shoulder & Other Joints; Autoimmune & Inflammatory Conditions |
Preclinical |
Preclinical – Animal / Veterinary |
Liu H |
2015 |
26414238 ↗ |
| Uterine-derived progenitor cells are immunoprivileged and effectively improve cardiac regeneration when used for cell therapy |
Heart & Circulation; How MSCs Work |
Preclinical |
Preclinical – Animal / Veterinary |
Ludke A |
2015 |
25939780 ↗ |
| Functional Reconstruction of Tracheal Defects by Protein-Loaded, Cell-Seeded, Fibrous Constructs in Rabbits |
Bone Healing & Osteonecrosis; Cell Quality, Manufacturing & Delivery |
Preclinical |
Preclinical – Animal / Veterinary |
Ott LM |
2015 |
26094554 ↗ |
| Mesenchymal stromal cells for cutaneous wound healing in a rabbit model: pre-clinical study applicable in the pediatric surgical setting |
Wound Healing & Skin Conditions |
Preclinical |
Preclinical – Animal / Veterinary |
Pelizzo G |
2015 |
26152232 ↗ |
| Repair of ear cartilage defects with allogenic bone marrow mesenchymal stem cells in rabbits |
Hip, Shoulder & Other Joints; Bone Healing & Osteonecrosis |
Preclinical |
Preclinical – Animal / Veterinary |
Cheng Y |
2014 |
24879616 ↗ |
| Immunogenicity of undifferentiated and differentiated allogeneic mouse mesenchymal stem cells |
Safety & Side Effects |
Preclinical |
Preclinical – Animal / Veterinary |
Mukonoweshuro B |
2014 |
24812582 ↗ |
| Mouse Flk-1+Sca-1- mesenchymal stem cells: functional plasticity in vitro and immunoregulation in vivo |
How MSCs Work |
Preclinical |
Preclinical – Animal / Veterinary |
Xishan Z |
2014 |
24487394 ↗ |
| Treatment of osteochondral defects in the rabbit's knee joint by implantation of allogeneic mesenchymal stem cells in fibrin clots |
Knee Arthritis; Hip, Shoulder & Other Joints; Cell Quality, Manufacturing & Delivery |
Preclinical |
Preclinical – Animal / Veterinary |
Berninger MT |
2013 |
23728213 ↗ |
| The effects of topical mesenchymal stem cell transplantation in canine experimental cutaneous wounds |
Wound Healing & Skin Conditions |
Preclinical |
Preclinical – Animal / Veterinary |
Kim JW |
2013 |
23432413 ↗ |
| Allogeneic mesenchymal stem cell therapy for bisphosphonate-related jaw osteonecrosis in Swine |
Bone Healing & Osteonecrosis |
Preclinical |
Preclinical – Animal / Veterinary |
Li Y |
2013 |
23461552 ↗ |
| Topical administration of allogeneic mesenchymal stromal cells seeded in a collagen scaffold augments wound healing and increases angiogenesis in the diabetic rabbit ulcer |
Wound Healing & Skin Conditions; Cell Quality, Manufacturing & Delivery |
Preclinical |
Preclinical – Animal / Veterinary |
O'Loughlin A |
2013 |
23423568 ↗ |
| Inflammatory effects of autologous, genetically modified autologous, allogeneic, and xenogeneic mesenchymal stem cells after intra-articular injection in horses |
Hip, Shoulder & Other Joints; Safety & Side Effects |
Preclinical |
Preclinical – Animal / Veterinary |
Pigott JH |
2013 |
24080668 ↗ |
| Investigation of the immune response to autologous, allogeneic, and xenogeneic mesenchymal stem cells after intra-articular injection in horses |
Hip, Shoulder & Other Joints; Safety & Side Effects; How MSCs Work |
Preclinical |
Preclinical – Animal / Veterinary |
Pigott JH |
2013 |
24094688 ↗ |
| Transplantation of bone marrow-derived mesenchymal stem cells promotes delayed wound healing in diabetic rats |
Wound Healing & Skin Conditions |
Preclinical |
Preclinical – Animal / Veterinary |
Wan J |
2013 |
23671884 ↗ |
| Mesenchymal stem cells combined with an artificial dermal substitute improve repair in full-thickness skin wounds |
Wound Healing & Skin Conditions; Cell Quality, Manufacturing & Delivery |
Preclinical |
Preclinical – Animal / Veterinary |
Leonardi D |
2012 |
22998897 ↗ |
| Mesenchymal stem cells improve the healing of ischemic colonic anastomoses (experimental study) |
Other Areas of MSC Research |
Preclinical |
Preclinical – Animal / Veterinary |
Adas G |
2011 |
20953879 ↗ |
| A preliminary study comparing the use of allogenic chondrogenic pre-differentiated and undifferentiated mesenchymal stem cells for the repair of full thickness articular cartilage defects in rabbits |
Hip, Shoulder & Other Joints |
Preclinical |
Preclinical – Animal / Veterinary |
Dashtdar H |
2011 |
21445989 ↗ |
| Autologous mesenchymal stem cells loaded in Gelfoam(®) for structural bone allograft healing in rabbits |
Bone Healing & Osteonecrosis; Cell Quality, Manufacturing & Delivery |
Preclinical |
Preclinical – Animal / Veterinary |
Lee JY |
2011 |
20652421 ↗ |
| Fate of bone marrow mesenchymal stem cells following the allogeneic transplantation of cartilaginous aggregates into osteochondral defects of rabbits |
Hip, Shoulder & Other Joints; Safety & Side Effects |
Preclinical |
Preclinical – Animal / Veterinary |
Yoshioka T |
2011 |
20799242 ↗ |
| Cervical motion preservation using mesenchymal progenitor cells and pentosan polysulfate, a novel chondrogenic agent: preliminary study in an ovine model |
Back Pain & Disc Disease |
Preclinical |
Preclinical – Animal / Veterinary |
Goldschlager T |
2010 |
20521963 ↗ |
| Mesenchymal stromal cells engineered to express erythropoietin induce anti-erythropoietin antibodies and anemia in allorecipients |
Safety & Side Effects; Cell Quality, Manufacturing & Delivery |
Preclinical |
Preclinical – Animal / Veterinary |
Campeau PM |
2009 |
19088705 ↗ |
| Analysis of allogenicity of mesenchymal stem cells in engraftment and wound healing in mice |
Transplant & Blood Disorders; Wound Healing & Skin Conditions |
Preclinical |
Preclinical – Animal / Veterinary |
Chen L |
2009 |
19771171 ↗ |
| Mesenchymal stem cells can affect solid organ allograft survival |
Transplant & Blood Disorders |
Preclinical |
Preclinical – Animal / Veterinary |
Popp FC |
2009 |
19424009 ↗ |
| Autologous and allogeneic marrow stromal cells are safe and effective for the treatment of acute kidney injury |
Other Areas of MSC Research; Safety & Side Effects |
Preclinical |
Preclinical – Animal / Veterinary |
Tögel F |
2009 |
18564903 ↗ |
| Mesenchymal stem cells improve outcomes of cardiopulmonary resuscitation in myocardial infarcted rats |
Heart & Circulation |
Preclinical |
Preclinical – Animal / Veterinary |
Wang T |
2009 |
19101561 ↗ |
| Mesenchymal stromal cells lose their immunosuppressive potential after allotransplantation |
How MSCs Work |
Preclinical |
Preclinical – Animal / Veterinary |
Prigozhina TB |
2008 |
18619727 ↗ |
| Feasibility of a stem cell therapy for intervertebral disc degeneration |
Back Pain & Disc Disease |
Preclinical |
Preclinical – Animal / Veterinary |
Sobajima S |
2008 |
18082460 ↗ |
| Transplantation of meniscus regenerated by tissue engineering with a scaffold derived from a rat meniscus and mesenchymal stromal cells derived from rat bone marrow |
Hip, Shoulder & Other Joints; Cell Quality, Manufacturing & Delivery |
Preclinical |
Preclinical – Animal / Veterinary |
Yamasaki T |
2008 |
18638305 ↗ |
| Soluble signalling factors derived from differentiated cartilage tissue affect chondrogenic differentiation of rat adult marrow stromal cells |
Hip, Shoulder & Other Joints |
Preclinical |
Preclinical – Animal / Veterinary |
Ahmed N |
2007 |
17762193 ↗ |
| Cell therapy using allogeneic bone marrow mesenchymal stem cells prevents tissue damage in collagen-induced arthritis |
Autoimmune & Inflammatory Conditions |
Preclinical |
Preclinical – Animal / Veterinary |
Augello A |
2007 |
17393437 ↗ |
| Mesenchymal stem cells enhance wound healing through differentiation and angiogenesis |
Wound Healing & Skin Conditions |
Preclinical |
Preclinical – Animal / Veterinary |
Wu Y |
2007 |
17615264 ↗ |
| Bone marrow-derived mesenchymal stromal cells accelerate wound healing in the rat |
Wound Healing & Skin Conditions |
Preclinical |
Preclinical – Animal / Veterinary |
McFarlin K |
2006 |
16939576 ↗ |
| [A comparative study of the dynamics of deep burns healing in using medullary allogenic fibroblast-like mesenchymal stem cells from bone marrow immobilized on biodegrading membranes or taken from cultural plastic] |
Wound Healing & Skin Conditions; Cell Quality, Manufacturing & Delivery |
Preclinical |
Preclinical – Animal / Veterinary |
Rasulov MF |
2005 |
16078651 ↗ |
| Mesenchymal bone marrow stem cells more effectively stimulate regeneration of deep burn wounds than embryonic fibroblasts |
Wound Healing & Skin Conditions |
Preclinical |
Preclinical – Animal / Veterinary |
Shumakov VI |
2003 |
14631508 ↗ |
| Migration of mesenchymal stem cells to heart allografts during chronic rejection |
Transplant & Blood Disorders; Safety & Side Effects |
Preclinical |
Preclinical – Animal / Veterinary |
Wu GD |
2003 |
12640309 ↗ |
| Juvenile Chondrocyte Cell Sheet Layering Enhances In Vitro Chondrogenic Differentiation |
Hip, Shoulder & Other Joints; Cell Quality, Manufacturing & Delivery |
Preclinical |
Basic Science / In Vitro |
Metzler NF |
2026 |
41619219 ↗ |
| Stage-specific MSC spheroid fusion enables bottom-up formation of stage-defined hierarchical cartilage graft |
Hip, Shoulder & Other Joints; Cell Quality, Manufacturing & Delivery |
Preclinical |
Basic Science / In Vitro |
Liu YL |
2026 |
42751092 ↗ |
| Comparison of the chondrogenic potential of eBMSCs and eUCMSCs in response to selected peptides and compounds |
Hip, Shoulder & Other Joints |
Preclinical |
Basic Science / In Vitro |
Ajeeb B |
2025 |
39956895 ↗ |
| HAMA-SBMA hydrogel with anti-inflammatory properties delivers cartilage organoids, boosting cartilage regeneration |
Hip, Shoulder & Other Joints; How MSCs Work; Cell Quality, Manufacturing & Delivery |
Preclinical |
Basic Science / In Vitro |
Gao Y |
2025 |
40448111 ↗ |
| Compositional editing of extracellular matrices by CRISPR/Cas9 engineering of human mesenchymal stem cell lines |
Cell Quality, Manufacturing & Delivery |
Preclinical |
Basic Science / In Vitro |
Prithiviraj S |
2025 |
40152921 ↗ |
| Allogeneic bone marrow mesenchymal stem cell-derived exosomes alleviate human hypoxic AKI-on-a-Chip within a tight treatment window |
Other Areas of MSC Research; Cell Sources & Treatment Comparisons |
Preclinical |
Basic Science / In Vitro |
Çam SB |
2024 |
38600585 ↗ |
| Low-intensity pulsed ultrasound (LIPUS) enhances the anti-inflammatory effects of bone marrow mesenchymal stem cells (BMSCs)-derived extracellular vesicles |
How MSCs Work; Cell Sources & Treatment Comparisons |
Preclinical |
Basic Science / In Vitro |
Li X |
2023 |
36717768 ↗ |
| IL-1b in the Secretomes of MSCs Seeded on Human Decellularized Allogeneic Bone Promotes Angiogenesis |
Cell Sources & Treatment Comparisons; Cell Quality, Manufacturing & Delivery |
Preclinical |
Basic Science / In Vitro |
Chen YC |
2022 |
36499629 ↗ |
| Hyaluronan size alters chondrogenesis of mesenchymal stem cells cultured on tricalcium phosphate-collagen-hyaluronan scaffolds |
Hip, Shoulder & Other Joints; Cell Quality, Manufacturing & Delivery |
Preclinical |
Basic Science / In Vitro |
Meng F |
2022 |
34859573 ↗ |
| MHC Class I Enables MSCs to Evade NK-Cell-Mediated Cytotoxicity and Exert Immunosuppressive Activity |
Safety & Side Effects; How MSCs Work |
Preclinical |
Basic Science / In Vitro |
Oh JY |
2022 |
35852488 ↗ |
| Human myoblasts differentiate in various mesenchymal lineages and inhibit allogeneic T cell proliferation through an indolamine 2,3 dioxygenase dependent pathway |
How MSCs Work; Cell Sources & Treatment Comparisons |
Preclinical |
Basic Science / In Vitro |
Kindler V |
2021 |
33839146 ↗ |
| Dexamethasone priming enhances stemness and immunomodulatory property of tissue-specific human mesenchymal stem cells |
How MSCs Work; Cell Quality, Manufacturing & Delivery |
Preclinical |
Basic Science / In Vitro |
Rawat S |
2021 |
34736395 ↗ |
| Effects of Normal Synovial Fluid and Interferon Gamma on Chondrogenic Capability and Immunomodulatory Potential Respectively on Equine Mesenchymal Stem Cells |
Hip, Shoulder & Other Joints; How MSCs Work |
Preclinical |
Basic Science / In Vitro |
Zayed M |
2021 |
34203758 ↗ |
| Functional Comparison between Healthy and Multiple Myeloma Adipose Stromal Cells |
Transplant & Blood Disorders; Cell Sources & Treatment Comparisons |
Preclinical |
Basic Science / In Vitro |
Espagnolle N |
2020 |
32215016 ↗ |
| Deciphering the Association of Cytokines, Chemokines, and Growth Factors in Chondrogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells Using an ex vivo Osteochondral Culture System |
Hip, Shoulder & Other Joints; How MSCs Work |
Preclinical |
Basic Science / In Vitro |
Jafri MA |
2020 |
32010693 ↗ |
| Cryopreserved, Thin, Laser-Etched Osteochondral Allograft maintains the functional components of articular cartilage after 2 years of storage |
Hip, Shoulder & Other Joints |
Preclinical |
Basic Science / In Vitro |
Rorick CB |
2020 |
33176819 ↗ |
| MMP13 and TIMP1 are functional markers for two different potential modes of action by mesenchymal stem/stromal cells when treating osteoarthritis |
Knee Arthritis; Hip, Shoulder & Other Joints; How MSCs Work |
Preclinical |
Basic Science / In Vitro |
Salerno A |
2020 |
32652878 ↗ |
| A Protocol for the Isolation, Culture, and Cryopreservation of Umbilical Cord-Derived Canine Mesenchymal Stromal Cells: Role of Cell Attachment in Long-Term Maintenance |
Cell Quality, Manufacturing & Delivery |
Preclinical |
Basic Science / In Vitro |
Wright A |
2020 |
32148170 ↗ |
| Regenerative Capacity of Adipose Derived Stem Cells (ADSCs), Comparison with Mesenchymal Stem Cells (MSCs) |
Cell Sources & Treatment Comparisons |
Preclinical |
Basic Science / In Vitro |
Mazini L |
2019 |
31121953 ↗ |
| Enhanced Antitumor Efficacy of Oncolytic Adenovirus-loaded Menstrual Blood-derived Mesenchymal Stem Cells in Combination with Peripheral Blood Mononuclear Cells |
Other Areas of MSC Research |
Preclinical |
Basic Science / In Vitro |
Moreno R |
2019 |
30322950 ↗ |
| Does the Harvesting Site Influence the Osteogenic Potential of Mesenchymal Stem Cells? |
Bone Healing & Osteonecrosis; Cell Sources & Treatment Comparisons |
Preclinical |
Basic Science / In Vitro |
Nguyen VT |
2019 |
31191688 ↗ |
| Osteopetrotic induced pluripotent stem cells derived from patients with different disease-associated mutations by non-integrating reprogramming methods |
Bone Healing & Osteonecrosis; Cell Sources & Treatment Comparisons |
Preclinical |
Basic Science / In Vitro |
Okur FV |
2019 |
31315669 ↗ |
| Paracrine Proangiogenic Function of Human Bone Marrow-Derived Mesenchymal Stem Cells Is Not Affected by Chronic Kidney Disease |
Other Areas of MSC Research; How MSCs Work |
Preclinical |
Basic Science / In Vitro |
van Rhijn-Brouwer FCC |
2019 |
31933648 ↗ |
| Hypoxia-induced 26S proteasome dysfunction increases immunogenicity of mesenchymal stem cells |
Safety & Side Effects; Cell Quality, Manufacturing & Delivery |
Preclinical |
Basic Science / In Vitro |
Abu-El-Rub E |
2019 |
30692516 ↗ |
| Potency Analysis of Mesenchymal Stromal Cells Using a Phospho-STAT Matrix Loop Analytical Approach |
Cell Quality, Manufacturing & Delivery |
Preclinical |
Basic Science / In Vitro |
Chinnadurai R |
2019 |
31108008 ↗ |
| Isolation and Characterization of a Human Fetal Mesenchymal Stem Cell Population: Exploring the Potential for Cell Banking in Wound Healing Therapies |
Wound Healing & Skin Conditions; Cell Sources & Treatment Comparisons; Cell Quality, Manufacturing & Delivery |
Preclinical |
Basic Science / In Vitro |
Esteban-Vives R |
2019 |
31407589 ↗ |
| Effect of culture duration on chondrogenic preconditioning of equine bone marrow mesenchymal stem cells in self-assembling peptide hydrogel |
Hip, Shoulder & Other Joints; Cell Quality, Manufacturing & Delivery |
Preclinical |
Basic Science / In Vitro |
Kisiday JD |
2019 |
30095195 ↗ |
| RNA sequencing of mesenchymal stem cells reveals a blocking of differentiation and immunomodulatory activities under inflammatory conditions in rheumatoid arthritis patients |
Autoimmune & Inflammatory Conditions; How MSCs Work |
Preclinical |
Basic Science / In Vitro |
Lamas JR |
2019 |
31060598 ↗ |
| Co-Culturing of Multipotent Mesenchymal Stromal Cells with Autological and Allogenic Lymphocytes |
How MSCs Work |
Preclinical |
Basic Science / In Vitro |
Kapranov NM |
2018 |
29504089 ↗ |
| N-acetyl-L-cysteine improves mesenchymal stem cell function in prolonged isolated thrombocytopenia post-allotransplant |
Transplant & Blood Disorders |
Preclinical |
Basic Science / In Vitro |
Kong Y |
2018 |
29392716 ↗ |
| Early passaging of mesenchymal stem cells does not instigate significant modifications in their immunological behavior |
How MSCs Work; Cell Quality, Manufacturing & Delivery |
Preclinical |
Basic Science / In Vitro |
Sareen N |
2018 |
29720263 ↗ |
| Epithelial In vitro Differentiation of Mesenchymal Stem Cells |
How MSCs Work |
Preclinical |
Basic Science / In Vitro |
Sierra-Sánchez Á |
2018 |
29714147 ↗ |
| Dysfunctional Bone Marrow Mesenchymal Stem Cells in Patients with Poor Graft Function after Allogeneic Hematopoietic Stem Cell Transplantation |
Transplant & Blood Disorders |
Preclinical |
Basic Science / In Vitro |
Song Y |
2018 |
29933074 ↗ |
| Mesenchymal Stromal/stem Cell-derived Extracellular Vesicles Promote Human Cartilage Regeneration In Vitro |
Hip, Shoulder & Other Joints; Cell Sources & Treatment Comparisons |
Preclinical |
Basic Science / In Vitro |
Vonk LA |
2018 |
29463990 ↗ |
| Differentiation of equine bone marrow derived mesenchymal stem cells increases the expression of immunogenic genes |
Safety & Side Effects |
Preclinical |
Basic Science / In Vitro |
Barrachina L |
2018 |
29776607 ↗ |
| Analysis of Mesenchymal Stromal Cell Engraftment After Allogeneic HSCT in Pediatric Patients: A Large Multicenter Study |
Transplant & Blood Disorders; Safety & Side Effects |
Preclinical |
Basic Science / In Vitro |
Castello LM |
2018 |
30188352 ↗ |
| Procoagulant activity of human mesenchymal stem cells |
Safety & Side Effects |
Preclinical |
Basic Science / In Vitro |
Christy BA |
2017 |
28628602 ↗ |
| Autologous and Allogeneic Equine Mesenchymal Stem Cells Exhibit Equivalent Immunomodulatory Properties In Vitro |
How MSCs Work |
Preclinical |
Basic Science / In Vitro |
Colbath AC |
2017 |
27958776 ↗ |
| Development of a surrogate potency assay to determine the angiogenic activity of Stempeucel®, a pooled, ex-vivo expanded, allogeneic human bone marrow mesenchymal stromal cell product |
Cell Quality, Manufacturing & Delivery |
Preclinical |
Basic Science / In Vitro |
Thej C |
2017 |
28245882 ↗ |
| Cell therapy in critical limb ischemia: A comprehensive analysis of two cell therapy products |
Heart & Circulation |
Preclinical |
Basic Science / In Vitro |
Tournois C |
2017 |
27914820 ↗ |
| Immunomodulatory function of whole human umbilical cord derived mesenchymal stem cells |
How MSCs Work |
Preclinical |
Basic Science / In Vitro |
Zhang H |
2017 |
28531813 ↗ |
| Effect of inflammatory environment on equine bone marrow derived mesenchymal stem cells immunogenicity and immunomodulatory properties |
Safety & Side Effects; How MSCs Work |
Preclinical |
Basic Science / In Vitro |
Barrachina L |
2016 |
26964718 ↗ |
| Protocols for in vitro Differentiation of Human Mesenchymal Stem Cells into Osteogenic, Chondrogenic and Adipogenic Lineages |
Cell Quality, Manufacturing & Delivery |
Preclinical |
Basic Science / In Vitro |
Ciuffreda MC |
2016 |
27236670 ↗ |
| Type 1 Diabetes Mellitus Donor Mesenchymal Stromal Cells Exhibit Comparable Potency to Healthy Controls In Vitro |
Other Areas of MSC Research; Cell Sources & Treatment Comparisons; Cell Quality, Manufacturing & Delivery |
Preclinical |
Basic Science / In Vitro |
Davies LC |
2016 |
27412884 ↗ |
| Characterization of HLA-G and Related Immunosuppressive Effects in Human Umbilical Cord Stroma-Derived Stem Cells |
How MSCs Work; Cell Sources & Treatment Comparisons |
Preclinical |
Basic Science / In Vitro |
Ding DC |
2016 |
26044082 ↗ |
| Mesenchymal Stem Cells Derived from Human Bone Marrow and Adipose Tissue Maintain Their Immunosuppressive Properties After Chondrogenic Differentiation: Role of HLA-G |
Hip, Shoulder & Other Joints; How MSCs Work; Cell Sources & Treatment Comparisons |
Preclinical |
Basic Science / In Vitro |
Du WJ |
2016 |
27465875 ↗ |
| Comparative study of equine mesenchymal stem cells from healthy and injured synovial tissues: an in vitro assessment |
Hip, Shoulder & Other Joints; Cell Sources & Treatment Comparisons |
Preclinical |
Basic Science / In Vitro |
Fülber J |
2016 |
26944403 ↗ |
| Cryopreservation and Revival of Human Mesenchymal Stromal Cells |
Cell Quality, Manufacturing & Delivery |
Preclinical |
Basic Science / In Vitro |
Haack-Sørensen M |
2016 |
27236683 ↗ |
| Mesenchymal Stromal Cells from Osteoarthritic Synovium Are a Distinct Population Compared to Their Bone-Marrow Counterparts regarding Surface Marker Distribution and Immunomodulation of Allogeneic CD4+ T-Cell Cultures |
Hip, Shoulder & Other Joints; How MSCs Work; Cell Sources & Treatment Comparisons |
Preclinical |
Basic Science / In Vitro |
Hagmann S |
2016 |
27516777 ↗ |
| The bone marrow microenvironment is similarly impaired in allogeneic hematopoietic stem cell transplantation patients with early and late poor graft function |
Transplant & Blood Disorders |
Preclinical |
Basic Science / In Vitro |
Kong Y |
2016 |
26437066 ↗ |
| Clinical-scale expansion of mesenchymal stromal cells: a large banking experience |
Cell Quality, Manufacturing & Delivery |
Preclinical |
Basic Science / In Vitro |
Lechanteur C |
2016 |
27207011 ↗ |
| Clinical-Grade Human Multipotent Adult Progenitor Cells Block CD8+ Cytotoxic T Lymphocytes |
How MSCs Work; Cell Quality, Manufacturing & Delivery |
Preclinical |
Basic Science / In Vitro |
Plessers J |
2016 |
27465071 ↗ |
| Quality Control Assays for Clinical-Grade Human Mesenchymal Stromal Cells: Methods for ATMP Release |
Other Areas of MSC Research; Cell Quality, Manufacturing & Delivery |
Preclinical |
Basic Science / In Vitro |
Radrizzani M |
2016 |
27236681 ↗ |
| Macro- and micro-designed chitosan-alginate scaffold architecture by three-dimensional printing and directional freezing |
Cell Quality, Manufacturing & Delivery |
Preclinical |
Basic Science / In Vitro |
Reed S |
2016 |
26741113 ↗ |
| Differentiation of Bone Marrow Mesenchymal Stem Cells in Osteoblasts and Adipocytes and its Role in Treatment of Osteoporosis |
Bone Healing & Osteonecrosis |
Preclinical |
Basic Science / In Vitro |
Wang C |
2016 |
26795027 ↗ |
| Ex vivo evaluation of acellular and cellular collagen-glycosaminoglycan flowable matrices |
Wound Healing & Skin Conditions; Cell Quality, Manufacturing & Delivery |
Preclinical |
Basic Science / In Vitro |
Hodgkinson T |
2015 |
26181360 ↗ |
| Different Procoagulant Activity of Therapeutic Mesenchymal Stromal Cells Derived from Bone Marrow and Placental Decidua |
Safety & Side Effects; Cell Quality, Manufacturing & Delivery |
Preclinical |
Basic Science / In Vitro |
Moll G |
2015 |
26192403 ↗ |
| Effects of simvastatin on the osteogenic differentiation and immunomodulation of bone marrow mesenchymal stem cells |
Bone Healing & Osteonecrosis; How MSCs Work |
Preclinical |
Basic Science / In Vitro |
Niu J |
2015 |
26499955 ↗ |
| Expression of genes involved in immune response and in vitro immunosuppressive effect of equine MSCs |
Safety & Side Effects; How MSCs Work |
Preclinical |
Basic Science / In Vitro |
Remacha AR |
2015 |
25977164 ↗ |
| Wound-healing potential of human umbilical cord blood-derived mesenchymal stromal cells in vitro–a pilot study |
Wound Healing & Skin Conditions |
Preclinical |
Basic Science / In Vitro |
You HJ |
2015 |
26212609 ↗ |
| Bone marrow mesenchymal stromal cells isolated from multiple sclerosis patients have distinct gene expression profile and decreased suppressive function compared with healthy counterparts |
Brain, Nerves & Neurological Conditions; Cell Sources & Treatment Comparisons |
Preclinical |
Basic Science / In Vitro |
de Oliveira GL |
2015 |
24256874 ↗ |
| Characterization of bone marrow-derived mesenchymal stem cells in aging |
Cell Sources & Treatment Comparisons; Cell Quality, Manufacturing & Delivery |
Preclinical |
Basic Science / In Vitro |
Baker N |
2015 |
25445445 ↗ |
| A reproducible immunopotency assay to measure mesenchymal stromal cell-mediated T-cell suppression |
How MSCs Work; Cell Quality, Manufacturing & Delivery |
Preclinical |
Basic Science / In Vitro |
Bloom DD |
2015 |
25455739 ↗ |
| Bone Marrow Mesenchymal Stromal Cells from Patients with Acute and Chronic Graft-versus-Host Disease Deploy Normal Phenotype, Differentiation Plasticity, and Immune-Suppressive Activity |
Transplant & Blood Disorders; Cell Sources & Treatment Comparisons |
Preclinical |
Basic Science / In Vitro |
Copland IB |
2015 |
25659882 ↗ |
| Examining the feasibility of clinical grade CD271+ enrichment of mesenchymal stromal cells for bone regeneration |
Bone Healing & Osteonecrosis; Cell Quality, Manufacturing & Delivery |
Preclinical |
Basic Science / In Vitro |
Cuthbert RJ |
2015 |
25760857 ↗ |
| Immunosuppressive properties of Wharton's jelly-derived mesenchymal stromal cells in vitro |
How MSCs Work |
Preclinical |
Basic Science / In Vitro |
He H |
2015 |
26228529 ↗ |
| In vivo detection of polyomaviruses JCV and SV40 in mesenchymal stem cells from human umbilical cords |
Safety & Side Effects |
Preclinical |
Basic Science / In Vitro |
Comar M |
2014 |
24623583 ↗ |
| Isolation, expansion and characterization of bone marrow-derived mesenchymal stromal cells in serum-free conditions |
Cell Sources & Treatment Comparisons; Cell Quality, Manufacturing & Delivery |
Preclinical |
Basic Science / In Vitro |
Gottipamula S |
2014 |
24448665 ↗ |
| Manufacturing and use of human placenta-derived mesenchymal stromal cells for phase I clinical trials: establishment and evaluation of a protocol |
Cell Sources & Treatment Comparisons; Cell Quality, Manufacturing & Delivery |
Preclinical |
Basic Science / In Vitro |
Ilić N |
2014 |
25109112 ↗ |
| Multipotent adult progenitor cells decrease cold ischemic injury in ex vivo perfused human lungs: an initial pilot and feasibility study |
Other Areas of MSC Research |
Preclinical |
Basic Science / In Vitro |
La Francesca S |
2014 |
25671090 ↗ |
| Detection of spontaneous tumorigenic transformation during culture expansion of human mesenchymal stromal cells |
Other Areas of MSC Research; Safety & Side Effects; Cell Quality, Manufacturing & Delivery |
Preclinical |
Basic Science / In Vitro |
Pan Q |
2014 |
24227633 ↗ |
| Establishing a bone marrow stromal cell transplant program at the National Institutes of Health Clinical Center |
Other Areas of MSC Research; Cell Quality, Manufacturing & Delivery |
Preclinical |
Basic Science / In Vitro |
Stroncek DF |
2014 |
24368014 ↗ |
| A CD8 T cell/indoleamine 2,3-dioxygenase axis is required for mesenchymal stem cell suppression of human systemic lupus erythematosus |
Autoimmune & Inflammatory Conditions; How MSCs Work |
Preclinical |
Basic Science / In Vitro |
Wang D |
2014 |
24756936 ↗ |
| The influence of bone marrow- and synovium-derived mesenchymal stromal cells from osteoarthritis patients on regulatory T cells in co-culture |
Knee Arthritis; Hip, Shoulder & Other Joints; How MSCs Work |
Preclinical |
Basic Science / In Vitro |
Hagmann S |
2013 |
23607395 ↗ |
| The use of adipose-derived stem cells as sheets for wound healing |
Wound Healing & Skin Conditions; Cell Quality, Manufacturing & Delivery |
Preclinical |
Basic Science / In Vitro |
McLaughlin MM |
2013 |
23764648 ↗ |
| Isolation and characterization of novel murine epiphysis derived mesenchymal stem cells |
Cell Sources & Treatment Comparisons; Cell Quality, Manufacturing & Delivery |
Preclinical |
Basic Science / In Vitro |
Cheng CC |
2012 |
22558340 ↗ |
| Human umbilical cord Wharton's jelly stem cells undergo enhanced chondrogenic differentiation when grown on nanofibrous scaffolds and in a sequential two-stage culture medium environment |
Hip, Shoulder & Other Joints; Cell Quality, Manufacturing & Delivery |
Preclinical |
Basic Science / In Vitro |
Fong CY |
2012 |
21671058 ↗ |
| Human MSC suppression correlates with cytokine induction of indoleamine 2,3-dioxygenase and bystander M2 macrophage differentiation |
How MSCs Work |
Preclinical |
Basic Science / In Vitro |
François M |
2012 |
21934657 ↗ |
| Impact of lenalidomide on the functional properties of human mesenchymal stromal cells |
Other Areas of MSC Research |
Preclinical |
Basic Science / In Vitro |
Wobus M |
2012 |
22705469 ↗ |
| Immunogenicity and immunomodulatory properties of umbilical cord lining mesenchymal stem cells |
Safety & Side Effects; How MSCs Work |
Preclinical |
Basic Science / In Vitro |
Deuse T |
2011 |
21054940 ↗ |
| Fetal and adult multipotent mesenchymal stromal cells are killed by different pathways |
How MSCs Work; Cell Sources & Treatment Comparisons |
Preclinical |
Basic Science / In Vitro |
Götherström C |
2011 |
20942778 ↗ |
| Transformation of human mesenchymal cells and skin fibroblasts into hematopoietic cells |
Safety & Side Effects |
Preclinical |
Basic Science / In Vitro |
Harris DM |
2011 |
21731684 ↗ |
| Mesenchymal stromal cells derived from CD271(+) bone marrow mononuclear cells exert potent allosuppressive properties |
How MSCs Work |
Preclinical |
Basic Science / In Vitro |
Kuçi Z |
2011 |
21905954 ↗ |
| A simple method for identifying bone marrow mesenchymal stromal cells with a high immunosuppressive potential |
How MSCs Work; Cell Quality, Manufacturing & Delivery |
Preclinical |
Basic Science / In Vitro |
Rizzo R |
2011 |
21171826 ↗ |
| Molecular profile and cellular characterization of human bone marrow mesenchymal stem cells: donor influence on chondrogenesis |
Hip, Shoulder & Other Joints; Cell Sources & Treatment Comparisons; Cell Quality, Manufacturing & Delivery |
Preclinical |
Basic Science / In Vitro |
Cicione C |
2010 |
20619527 ↗ |
| Characterization of mesenchymal stem cells isolated from the rabbit fetal liver |
Other Areas of MSC Research; Cell Sources & Treatment Comparisons |
Preclinical |
Basic Science / In Vitro |
Moreno R |
2010 |
20148649 ↗ |
| Phenotypical/functional characterization of in vitro-expanded mesenchymal stromal cells from patients with Crohn's disease |
Other Areas of MSC Research; Cell Sources & Treatment Comparisons |
Preclinical |
Basic Science / In Vitro |
Bernardo ME |
2009 |
19903096 ↗ |
| Amniotic mesenchymal tissue cells inhibit dendritic cell differentiation of peripheral blood and amnion resident monocytes |
How MSCs Work |
Preclinical |
Basic Science / In Vitro |
Magatti M |
2009 |
19523334 ↗ |
| FluidMAG iron nanoparticle-labeled mesenchymal stem cells for tracking cell homing to tumors |
Other Areas of MSC Research; Safety & Side Effects |
Preclinical |
Basic Science / In Vitro |
Shan L |
2009 |
20641467 ↗ |
| Poly(N,N-dimethylacrylamide)-coated maghemite nanoparticles for labeling and tracking mesenchymal stem cells |
Safety & Side Effects |
Preclinical |
Basic Science / In Vitro |
Shan L |
2009 |
20641410 ↗ |
| Amine-modified silica-coated polyhedral superparamagnetic iron oxide nanoparticle–labeled rabbit bone marrow–derived mesenchymal stem cells |
Safety & Side Effects |
Preclinical |
Basic Science / In Vitro |
Shan L |
2009 |
20641854 ↗ |
| Multimodal, rhodamine B isothiocyanate-incorporated, silica-coated magnetic nanoparticle–labeled human cord blood–derived mesenchymal stem cells for cell tracking |
Safety & Side Effects |
Preclinical |
Basic Science / In Vitro |
Shan L |
2009 |
20641578 ↗ |
| Immunogenicity of umbilical cord tissue derived cells |
Safety & Side Effects |
Preclinical |
Basic Science / In Vitro |
Cho PS |
2008 |
17909081 ↗ |
| Human palatine tonsil: a new potential tissue source of multipotent mesenchymal progenitor cells |
Cell Sources & Treatment Comparisons |
Preclinical |
Basic Science / In Vitro |
Janjanin S |
2008 |
18662393 ↗ |
| Characterization of a mesenchymal-like stem cell population from osteophyte tissue |
Cell Sources & Treatment Comparisons |
Preclinical |
Basic Science / In Vitro |
Singh S |
2008 |
18447640 ↗ |
| Immunosuppressive effects of mesenchymal stem cells: involvement of HLA-G |
How MSCs Work |
Preclinical |
Basic Science / In Vitro |
Nasef A |
2007 |
17667815 ↗ |
| Placenta-derived multipotent cells exhibit immunosuppressive properties that are enhanced in the presence of interferon-gamma |
How MSCs Work; Cell Sources & Treatment Comparisons |
Preclinical |
Basic Science / In Vitro |
Chang CJ |
2006 |
17071860 ↗ |
| In vitro analysis of multipotent mesenchymal stromal cells as potential cellular therapeutics in neurometabolic diseases in pediatric patients |
Brain, Nerves & Neurological Conditions |
Preclinical |
Basic Science / In Vitro |
Müller I |
2006 |
16982334 ↗ |
| Cell culture medium composition and translational adult bone marrow-derived stem cell research |
Cell Quality, Manufacturing & Delivery |
Preclinical |
Basic Science / In Vitro |
Sotiropoulou PA |
2006 |
16439613 ↗ |
| Repair of injured articular and growth plate cartilage using mesenchymal stem cells and chondrogenic gene therapy |
Hip, Shoulder & Other Joints |
Preclinical |
Basic Science / In Vitro |
Xian CJ |
2006 |
18220868 ↗ |
| Human mesenchymal stem cells inhibit differentiation and function of monocyte-derived dendritic cells |
How MSCs Work |
Preclinical |
Basic Science / In Vitro |
Jiang XX |
2005 |
15692068 ↗ |
| Multipotent mesenchymal stem cells with immunosuppressive activity can be easily isolated from dental pulp |
Other Areas of MSC Research; How MSCs Work; Cell Sources & Treatment Comparisons |
Preclinical |
Basic Science / In Vitro |
Pierdomenico L |
2005 |
16210973 ↗ |
| Immunologic properties of human fetal mesenchymal stem cells |
How MSCs Work; Cell Sources & Treatment Comparisons |
Preclinical |
Basic Science / In Vitro |
Götherström C |
2004 |
14749666 ↗ |
| Allogene Transplantationsmöglichkeiten humaner mesenchymaler Stammzellen. Eine In-vitro-Studie zur Knochenregeneration [Allogenic transplantation of human mesenchymal stem cells for tissue engineering purposes: an in vitro study] |
Bone Healing & Osteonecrosis; Cell Quality, Manufacturing & Delivery |
Preclinical |
Basic Science / In Vitro |
Niemeyer P |
2004 |
15578255 ↗ |
| Isolation of mouse marrow mesenchymal progenitors by a novel and reliable method |
Cell Quality, Manufacturing & Delivery |
Preclinical |
Basic Science / In Vitro |
Sun S |
2003 |
12968107 ↗ |
| Mesenchymal stem cells inhibit and stimulate mixed lymphocyte cultures and mitogenic responses independently of the major histocompatibility complex |
How MSCs Work |
Preclinical |
Basic Science / In Vitro |
Le Blanc K |
2003 |
12542793 ↗ |